Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco

A green methodology was developed for the analysis of ten heterocyclic aromatic amines (HAAs) in biomass samples from cigarette combustion such as mainstream smoke, paper ashes, as well as tobacco and paper wraps. The cellulose filter used for sample collection was also evaluated. This strategy was...

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Autores principales: Canales, Romina, Guiñez, María, Talio, Carolina, Reta, Mario Roberto, Cerutti, Soledad
Formato: Articulo
Lenguaje:Inglés
Publicado: 2020
Materias:
Ciencias Exactas
Química
Heterocyclic aromatic amines
UAE-MWCNT-based SPE
Mainstream smoke
Paper ashes
Tobacco
Green Certificate
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/132753
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-132753
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Química
Heterocyclic aromatic amines
UAE-MWCNT-based SPE
Mainstream smoke
Paper ashes
Tobacco
Green Certificate
spellingShingle Ciencias Exactas
Química
Heterocyclic aromatic amines
UAE-MWCNT-based SPE
Mainstream smoke
Paper ashes
Tobacco
Green Certificate
Canales, Romina
Guiñez, María
Talio, Carolina
Reta, Mario Roberto
Cerutti, Soledad
Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
topic_facet Ciencias Exactas
Química
Heterocyclic aromatic amines
UAE-MWCNT-based SPE
Mainstream smoke
Paper ashes
Tobacco
Green Certificate
description A green methodology was developed for the analysis of ten heterocyclic aromatic amines (HAAs) in biomass samples from cigarette combustion such as mainstream smoke, paper ashes, as well as tobacco and paper wraps. The cellulose filter used for sample collection was also evaluated. This strategy was based on ultrasound-assisted extraction (UAE) associated with a solid-phase extraction procedure employing multi-walled carbon nanotubes (MWCNTs-SPE) as a cleanup step followed by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). Under optimal experimental conditions, the linearity of the method was in the range from 0.08 to 160 ng cig-1, with correlation coefficients (R2) higher than 0.991. The limits of detection resulted to be between 0.03 and 0.63 ng cig-1. Concentrations of the HAAs in the mainstream smoke were from 5.7 to 145.2 ng cig-1 and in paper ashes from 0.1 to 0.6 ng cig -1, while in tobacco were between 1.0 and 38.5 ng cig-1. Meanwhile, no HAA contribution was observed in the case of paper wraps and the filter used for sample collection. The knowledge of the presence and the concentration levels of the selected HAAs in each cigarette’s physical component after its combustion is essential to understand the formation processes and contribution during cigarette burning. Besides, this is the first report about the presence of some HAAs in the proposed samples. Finally, a comparative study was employed to classify the sustainability of several recent approaches for HAA extraction from cigarette combustion samples using Green Certificate as a metric tool.
format Articulo
Articulo
author Canales, Romina
Guiñez, María
Talio, Carolina
Reta, Mario Roberto
Cerutti, Soledad
author_facet Canales, Romina
Guiñez, María
Talio, Carolina
Reta, Mario Roberto
Cerutti, Soledad
author_sort Canales, Romina
title Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
title_short Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
title_full Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
title_fullStr Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
title_full_unstemmed Development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
title_sort development of a green and efficient methodology for the heterocyclic aromatic amine determination in biomass samples generated from cigarette combustion and tobacco
publishDate 2020
url http://sedici.unlp.edu.ar/handle/10915/132753
work_keys_str_mv AT canalesromina developmentofagreenandefficientmethodologyfortheheterocyclicaromaticaminedeterminationinbiomasssamplesgeneratedfromcigarettecombustionandtobacco
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