Chromosomal breakpoints and changes in DNA copy number in refractory acute myeloid leukemia

Comparative genomic hybridization (CGH) was used to detect changes in DNA copy number in 25 cases of refractory acute myeloid leukemia (AML). CGH detected changes in DNA copy number in nine AML (36%). Losses (82%) were more frequent than gains (18%). No high-level amplifications were detected in any...

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Detalles Bibliográficos
Autores principales: El-Rifai, Wael, Elonen, Erkki, Larramendy, Marcelo Luis, Ruutu, Tapani, Knuutila, Sakari
Formato: Articulo
Lenguaje:Inglés
Publicado: 1997
Materias:
Biología
Ciencias Médicas
CGH
refractory AML
5q; 7q
12p
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/132500
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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