Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility

The work reported here describes the application of the optical technique known as dynamic speckle interferometry to evaluate the motility of nematode parasites exposed to different anthelmintic drugs. This technique, a well proven tool for assessing the time evolution of different phenomena, is her...

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Detalles Bibliográficos
Autores principales: Pomarico, J. A., Di Rocco, Héctor Oscar, Alvarez, L., Lanusse, Carlos E., Mottier, L., Saumell, C., Arizaga, Ricardo Augusto, Rabal, Héctor Jorge, Trivi, Marcelo Ricardo
Formato: Articulo
Lenguaje:Inglés
Publicado: 2004
Materias:
Ingeniería
Ciencias Exactas
Parasites
Pharmacodynamics
Speckle
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/131639
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-131639
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ingeniería
Ciencias Exactas
Parasites
Pharmacodynamics
Speckle
spellingShingle Ingeniería
Ciencias Exactas
Parasites
Pharmacodynamics
Speckle
Pomarico, J. A.
Di Rocco, Héctor Oscar
Alvarez, L.
Lanusse, Carlos E.
Mottier, L.
Saumell, C.
Arizaga, Ricardo Augusto
Rabal, Héctor Jorge
Trivi, Marcelo Ricardo
Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
topic_facet Ingeniería
Ciencias Exactas
Parasites
Pharmacodynamics
Speckle
description The work reported here describes the application of the optical technique known as dynamic speckle interferometry to evaluate the motility of nematode parasites exposed to different anthelmintic drugs. This technique, a well proven tool for assessing the time evolution of different phenomena, is here successfully used to quantify parasite motility in pharmacodynamic assays. The characterization of the pharmacological properties of anthelmintic drugs is critical to optimize their use in parasite control. Besides, the evaluation of nematode motility is a relevant indicator of the pharmacodynamic effect of anthelmintic drugs. The application of this approach to study the motility of <i>Haemonchus contortus</i> (used as a model of nematode parasites) larvae exposed to different drugs is presented, showing its usefulness.
format Articulo
Articulo
author Pomarico, J. A.
Di Rocco, Héctor Oscar
Alvarez, L.
Lanusse, Carlos E.
Mottier, L.
Saumell, C.
Arizaga, Ricardo Augusto
Rabal, Héctor Jorge
Trivi, Marcelo Ricardo
author_facet Pomarico, J. A.
Di Rocco, Héctor Oscar
Alvarez, L.
Lanusse, Carlos E.
Mottier, L.
Saumell, C.
Arizaga, Ricardo Augusto
Rabal, Héctor Jorge
Trivi, Marcelo Ricardo
author_sort Pomarico, J. A.
title Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
title_short Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
title_full Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
title_fullStr Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
title_full_unstemmed Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
title_sort speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility
publishDate 2004
url http://sedici.unlp.edu.ar/handle/10915/131639
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