Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits

The accumulation of 17 human pharmaceuticals (HPs) was investigated in the muscle of three fish species characteristic of the “Rio de la Plata Basin” with different feeding habits and of relevance for human consumption: Megaleporinus obtusidens, Salminus brasiliensis, and Prochilodus lineatus. Fish...

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Autores principales: Rojo, Macarena Gisele, Álvarez Muñoz, Diana, Dománico, Alejandro Arturo, Foti, R., Rodríguez Mozaz, Sara, Barceló, Damià, Carriquiriborde, Pedro
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2019
Materias:
Ecología
Ciencias Naturales
Emerging pollutants
Neotropical fish
Rio de la Plata Basin
Biomagnification
Health risk
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/131400
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-131400
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ecología
Ciencias Naturales
Emerging pollutants
Neotropical fish
Rio de la Plata Basin
Biomagnification
Health risk
spellingShingle Ecología
Ciencias Naturales
Emerging pollutants
Neotropical fish
Rio de la Plata Basin
Biomagnification
Health risk
Rojo, Macarena Gisele
Álvarez Muñoz, Diana
Dománico, Alejandro Arturo
Foti, R.
Rodríguez Mozaz, Sara
Barceló, Damià
Carriquiriborde, Pedro
Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits
topic_facet Ecología
Ciencias Naturales
Emerging pollutants
Neotropical fish
Rio de la Plata Basin
Biomagnification
Health risk
description The accumulation of 17 human pharmaceuticals (HPs) was investigated in the muscle of three fish species characteristic of the “Rio de la Plata Basin” with different feeding habits and of relevance for human consumption: Megaleporinus obtusidens, Salminus brasiliensis, and Prochilodus lineatus. Fish were sampled in fall and spring from 8 localities distributed along 500 Km of the Uruguay River. Atenolol and carbamazepine were the most frequently detected HPs (>50%), but at concentrations always below 1 μg/kg wet weight (w/w). Hydrochlorothiazide, metoprolol, venlafaxine, propranolol, codeine, and the carbamazepine metabolite, 2-hydroxycarbamazepine, were accumulated at higher levels showing maximum concentrations between 1 and 10 μg/kg (w/w), but infrequently (<50%). The other HPs were always below 1 μg/kg (w/w) and at frequencies lower than 50%. Distinctive accumulation patterns were observed among species at different trophic levels. However, biomagnification trends were not identified for any compound. The highest number and concentration of HPs were found in M. obtusidens (omnivorous), followed by P. lineatus (detritivorous), and lastly S. brasiliensis (piscivorous). The most recurrent HPs (i.e. carbamazepine and atenolol) were present in all species, but others exclusively in one. Geographical variations were only found for carbamazepine and atenolol in M. obtusidens and P. lineatus, showing higher concentrations in localities closer to the Rio de la Plata estuary. Differences in the HPs concentrations among seasons were not identified. Acceptable daily intake and predicted no effect concentrations would indicate that measured muscle concentrations in fish from the Uruguay River do not pose a serious risk for human consumption nowadays. Further studies will be necessary for assessing the potential adverse effects on studied fish species.
format Articulo
Preprint
author Rojo, Macarena Gisele
Álvarez Muñoz, Diana
Dománico, Alejandro Arturo
Foti, R.
Rodríguez Mozaz, Sara
Barceló, Damià
Carriquiriborde, Pedro
author_facet Rojo, Macarena Gisele
Álvarez Muñoz, Diana
Dománico, Alejandro Arturo
Foti, R.
Rodríguez Mozaz, Sara
Barceló, Damià
Carriquiriborde, Pedro
author_sort Rojo, Macarena Gisele
title Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits
title_short Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits
title_full Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits
title_fullStr Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits
title_full_unstemmed Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits
title_sort human pharmaceuticals in three major fish species from the uruguay river (south america) with different feeding habits
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/131400
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