Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation

Lipid peroxidation is generally thought to be a major mechanism of cell injury in aerobic organisms subjected to oxidative stress. All cellular membranes are especially vulnerable to oxidation due to their high concentration of polyunsaturated fatty acids. However, birds have special adaptations for...

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Autores principales: Gavazza, Mariana Beatriz, Marmunti, Monica Edith, Montalti, Diego, Gutiérrez, Ana María
Formato: Articulo
Lenguaje:Inglés
Publicado: 2008
Materias:
Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/131273
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-131273
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
spellingShingle Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
Gavazza, Mariana Beatriz
Marmunti, Monica Edith
Montalti, Diego
Gutiérrez, Ana María
Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
topic_facet Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
description Lipid peroxidation is generally thought to be a major mechanism of cell injury in aerobic organisms subjected to oxidative stress. All cellular membranes are especially vulnerable to oxidation due to their high concentration of polyunsaturated fatty acids. However, birds have special adaptations for preventing membrane damage caused by reactive oxygen species. This study examines fatty acid profiles and susceptibility to lipid peroxidation in liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>). The saturated fatty acids in these organelles represent approximately 40–50% of total fatty acids whereas the polyunsaturated fatty acid composition was highly distinctive, characterized by almost equal amounts of 18:2 n-6; 20:4n-6 and 22:6 n-3 in liver mitochondria, and a higher proportion of 18:2 n-6 compared to 20:4n-6 and 22:6 n-3 in heart mitochondria. The concentration of total unsaturated fatty acids of liver and heart mitochondria was approximately 50% and 60%, respectively, with a prevalence of oleic acid C18:1 n9. The rate C20:4 n6 / C18:2 n6 and the unsaturation index was similar in liver and heart mitochondria; 104.33 ± 6.73 and 100.09 ± 3.07, respectively. Light emission originating from these organelles showed no statistically significant differences and the polyunsaturated fatty acid profiles did not change during the lipid peroxidation process.
format Articulo
Articulo
author Gavazza, Mariana Beatriz
Marmunti, Monica Edith
Montalti, Diego
Gutiérrez, Ana María
author_facet Gavazza, Mariana Beatriz
Marmunti, Monica Edith
Montalti, Diego
Gutiérrez, Ana María
author_sort Gavazza, Mariana Beatriz
title Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_short Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_full Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_fullStr Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_full_unstemmed Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_sort liver and heart mitochondria obtained from adelie penguin (<i>pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
publishDate 2008
url http://sedici.unlp.edu.ar/handle/10915/131273
work_keys_str_mv AT gavazzamarianabeatriz liverandheartmitochondriaobtainedfromadeliepenguinipygoscelisadeliaeioffershighresistancetolipidperoxidation
AT marmuntimonicaedith liverandheartmitochondriaobtainedfromadeliepenguinipygoscelisadeliaeioffershighresistancetolipidperoxidation
AT montaltidiego liverandheartmitochondriaobtainedfromadeliepenguinipygoscelisadeliaeioffershighresistancetolipidperoxidation
AT gutierrezanamaria liverandheartmitochondriaobtainedfromadeliepenguinipygoscelisadeliaeioffershighresistancetolipidperoxidation
bdutipo_str Repositorios
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