Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

Flagella contribute to the virulence of pathogenic bacteria through chemotaxis, adhesion to and invasion of host surfaces. Flagellin is the structural protein that forms the major portion of flagellar filaments. Thus, flagellin consists of a conserved domain that is widespread in bacterial species a...

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Detalles Bibliográficos
Autores principales:	Cruz Ramos, Hugo, Rumbo, Martín, Sirard, Jean-Claude
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2004
Materias:	Ciencias Exactas flagella pathogenic bacteria Bacteria mucosal tissues
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/128918
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-128918
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Exactas flagella pathogenic bacteria Bacteria mucosal tissues
spellingShingle	Ciencias Exactas flagella pathogenic bacteria Bacteria mucosal tissues Cruz Ramos, Hugo Rumbo, Martín Sirard, Jean-Claude Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
topic_facet	Ciencias Exactas flagella pathogenic bacteria Bacteria mucosal tissues
description	Flagella contribute to the virulence of pathogenic bacteria through chemotaxis, adhesion to and invasion of host surfaces. Flagellin is the structural protein that forms the major portion of flagellar filaments. Thus, flagellin consists of a conserved domain that is widespread in bacterial species and is dedicated to filament polymerization. Conversely, mammalian hosts detect the conserved domain on flagellin monomers through Toll-like receptor (TLR) 5, which triggers proinflammatory and adaptive immune responses. This review describes the relationships among flagellin molecular structure, bacterial virulence and host defenses, with special emphasis on mucosal tissues.
format	Articulo Articulo
author	Cruz Ramos, Hugo Rumbo, Martín Sirard, Jean-Claude
author_facet	Cruz Ramos, Hugo Rumbo, Martín Sirard, Jean-Claude
author_sort	Cruz Ramos, Hugo
title	Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
title_short	Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
title_full	Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
title_fullStr	Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
title_full_unstemmed	Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
title_sort	bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
publishDate	2004
url	http://sedici.unlp.edu.ar/handle/10915/128918
work_keys_str_mv	AT cruzramoshugo bacterialflagellinsmediatorsofpathogenicityandhostimmuneresponsesinmucosa AT rumbomartin bacterialflagellinsmediatorsofpathogenicityandhostimmuneresponsesinmucosa AT sirardjeanclaude bacterialflagellinsmediatorsofpathogenicityandhostimmuneresponsesinmucosa
bdutipo_str	Repositorios
_version_	1764820451681370115

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

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