Fatal canine encephalitozoonosis in Latin America, first report

Encephalitozoon cuniculi is an obligate, intracellular microsporidian organism capable of establish infection in a wide variety of animals. In carnivores it may cause a sporadic, severe disease in the first few months of life, which usually culminates with the death of the animal. The objective of t...

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Autores principales: Postma, Gabriela Cintia, Pardini, Lais Luján, Carnevale, Silvana, Gregnoli, Elena, Quiroga, María Alejandra, Venturini, María Cecilia, Minatel, Leonardo
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2018
Materias:
Ciencias Veterinarias
Encephalitozoon cuniculi
Canine
Puppy
Encephalitis
Nephritis
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/128731
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-128731
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Encephalitozoon cuniculi
Canine
Puppy
Encephalitis
Nephritis
spellingShingle Ciencias Veterinarias
Encephalitozoon cuniculi
Canine
Puppy
Encephalitis
Nephritis
Postma, Gabriela Cintia
Pardini, Lais Luján
Carnevale, Silvana
Gregnoli, Elena
Quiroga, María Alejandra
Venturini, María Cecilia
Minatel, Leonardo
Fatal canine encephalitozoonosis in Latin America, first report
topic_facet Ciencias Veterinarias
Encephalitozoon cuniculi
Canine
Puppy
Encephalitis
Nephritis
description Encephalitozoon cuniculi is an obligate, intracellular microsporidian organism capable of establish infection in a wide variety of animals. In carnivores it may cause a sporadic, severe disease in the first few months of life, which usually culminates with the death of the animal. The objective of this study was to report a natural fatal case of encephalitozoonosis in a puppy from Argentina. Clinical signs included reduced appetite, depression, vocalizing, weight loss, weakness, convulsions and recumbency. No significant gross lesions were noticed at necropsy. Microscopically, severe, diffuse, lymphocytic encephalitis was seen. Large cytoplasmic vacuoles containing spores, morphologically compatible with E. cuniculi, were present within endothelial cells of brain and kidney, in renal tubular epithelium and hepatocytes. Encephalitozoon cuniculi DNA was detected by PCR in the kidney. Antibody titers to E. cuniculi in serum from the surviving puppies and the dam were ≥ 1:200. This report contributes to our understanding of neurologic disease in puppies. Encephalitozoonosis should be considered as a differential diagnosis in cases of fatal encephalitis in puppies.
format Articulo
Preprint
author Postma, Gabriela Cintia
Pardini, Lais Luján
Carnevale, Silvana
Gregnoli, Elena
Quiroga, María Alejandra
Venturini, María Cecilia
Minatel, Leonardo
author_facet Postma, Gabriela Cintia
Pardini, Lais Luján
Carnevale, Silvana
Gregnoli, Elena
Quiroga, María Alejandra
Venturini, María Cecilia
Minatel, Leonardo
author_sort Postma, Gabriela Cintia
title Fatal canine encephalitozoonosis in Latin America, first report
title_short Fatal canine encephalitozoonosis in Latin America, first report
title_full Fatal canine encephalitozoonosis in Latin America, first report
title_fullStr Fatal canine encephalitozoonosis in Latin America, first report
title_full_unstemmed Fatal canine encephalitozoonosis in Latin America, first report
title_sort fatal canine encephalitozoonosis in latin america, first report
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/128731
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bdutipo_str Repositorios
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