Amaranth as a Source of Antihypertensive Peptides

Amaranth is an ancestral crop used by pre-Columbian cultures for 6000 to 8000 years. Its grains have a relevant chemical composition not only from a nutritional point of view but also due to the contribution of components with good techno-functional properties and important potential as bioactive co...

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Detalles Bibliográficos
Autores principales:	Nardo, Agustina Estefanía, Suárez, Santiago E., Quiroga, Alejandra Viviana, Añón, María Cristina
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2020
Materias:	Ciencias Exactas amaranth hypertension bioactivity peptides mechanisms of action
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/128608
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Exactas amaranth hypertension bioactivity peptides mechanisms of action
spellingShingle	Ciencias Exactas amaranth hypertension bioactivity peptides mechanisms of action Nardo, Agustina Estefanía Suárez, Santiago E. Quiroga, Alejandra Viviana Añón, María Cristina Amaranth as a Source of Antihypertensive Peptides
topic_facet	Ciencias Exactas amaranth hypertension bioactivity peptides mechanisms of action
description	Amaranth is an ancestral crop used by pre-Columbian cultures for 6000 to 8000 years. Its grains have a relevant chemical composition not only from a nutritional point of view but also due to the contribution of components with good techno-functional properties and important potential as bioactive compounds. Numerous studies have shown that amaranth storage proteins possess encrypted sequences that, once released, exhibit different physiological activities. One of the most studied is antihypertensive activity. This review summarizes the progress made over the last years (2008-2020) related to this topic. Studies related to inhibition of different enzymes of the Renin-Angiotensin-Aldosterone system, in particular Angiotensin Converting Enzyme (ACE) and Renin, as well as those referring to potential modulation mechanisms of tissue or local Renin-Angiotensin-Aldosterone system, are analyzed, including <i>in silico</i>, <i>in vitro</i>, <i>in vivo</i>, and <i>ex vivo</i> assays. Furthermore, the potential use of these bioactive peptides or products containing them, in the elaboration of functional food matrices is discussed. Finally, the most relevant conclusions and future requirements in research and development of food products are presented.
format	Articulo Articulo
author	Nardo, Agustina Estefanía Suárez, Santiago E. Quiroga, Alejandra Viviana Añón, María Cristina
author_facet	Nardo, Agustina Estefanía Suárez, Santiago E. Quiroga, Alejandra Viviana Añón, María Cristina
author_sort	Nardo, Agustina Estefanía
title	Amaranth as a Source of Antihypertensive Peptides
title_short	Amaranth as a Source of Antihypertensive Peptides
title_full	Amaranth as a Source of Antihypertensive Peptides
title_fullStr	Amaranth as a Source of Antihypertensive Peptides
title_full_unstemmed	Amaranth as a Source of Antihypertensive Peptides
title_sort	amaranth as a source of antihypertensive peptides
publishDate	2020
url	http://sedici.unlp.edu.ar/handle/10915/128608
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bdutipo_str	Repositorios
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Amaranth as a Source of Antihypertensive Peptides

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