Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus

To grow and develop insects must undergo ecdysis. During this process, the individual sheds the old cuticle to emerge as the following developmental stage. During ecdysis, different programed behaviors are regulated by neuropeptidergic pathways. In general, components of these pathways are better ch...

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Autores principales: Wulff, Juan Pedro, Sierra, Ivana Samanta, Sterkel, Marcos, Holtof, Michiel, Van Wielendaele, Pieter, Francini, Flavio, Vanden Broeck, Jozef, Ons, Sheila
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Bioquímica
Chagas' disease
Post-embryonic development
Molting
Brain-gut neuropeptides
RNA interference (RNAi)
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/128373
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-128373
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Bioquímica
Chagas' disease
Post-embryonic development
Molting
Brain-gut neuropeptides
RNA interference (RNAi)
spellingShingle Bioquímica
Chagas' disease
Post-embryonic development
Molting
Brain-gut neuropeptides
RNA interference (RNAi)
Wulff, Juan Pedro
Sierra, Ivana Samanta
Sterkel, Marcos
Holtof, Michiel
Van Wielendaele, Pieter
Francini, Flavio
Vanden Broeck, Jozef
Ons, Sheila
Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
topic_facet Bioquímica
Chagas' disease
Post-embryonic development
Molting
Brain-gut neuropeptides
RNA interference (RNAi)
description To grow and develop insects must undergo ecdysis. During this process, the individual sheds the old cuticle to emerge as the following developmental stage. During ecdysis, different programed behaviors are regulated by neuropeptidergic pathways. In general, components of these pathways are better characterized in crustacean and holometabolous insects than in hemimetabola. In insects, the orkoninin gene produces two different neuropeptide precursors by alternative splicing: orcokinin A and orcokinin B. Although orcokinins are well conserved in insect species, their physiological role remains elusive. Here we describe a new splicing variant of the orcokinin gene in the hemimetabolous triatomine Rhodnius prolixus. We further analyze the expression pattern and the function of the alternatively spliced RhoprOK transcripts by means of immunohistochemistry and RNAi-mediated gene silencing. Our results indicate that orkoninis play an essential role in the peptidergic signaling pathway regulating ecdysis in the hemimetabolous insect Rhodnius prolixus.
format Articulo
Articulo
author Wulff, Juan Pedro
Sierra, Ivana Samanta
Sterkel, Marcos
Holtof, Michiel
Van Wielendaele, Pieter
Francini, Flavio
Vanden Broeck, Jozef
Ons, Sheila
author_facet Wulff, Juan Pedro
Sierra, Ivana Samanta
Sterkel, Marcos
Holtof, Michiel
Van Wielendaele, Pieter
Francini, Flavio
Vanden Broeck, Jozef
Ons, Sheila
author_sort Wulff, Juan Pedro
title Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
title_short Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
title_full Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
title_fullStr Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
title_full_unstemmed Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
title_sort orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect rhodnius prolixus
publishDate 2017
url http://sedici.unlp.edu.ar/handle/10915/128373
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AT sierraivanasamanta orcokininneuropeptidesregulateecdysisinthehemimetabolousinsectrhodniusprolixus
AT sterkelmarcos orcokininneuropeptidesregulateecdysisinthehemimetabolousinsectrhodniusprolixus
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