Metastatic dissemination with special emphasis on breast cancer cutaneous metastases

Metastatic development is a complex, multistage process involving modulation of cell phenotype, cell migration, and dynamic homeotypic as well as heterotypic cell-cell interactions. In breast cancer, MUC1 mucin has been emerging as a key molecule involved in metastasis. MUC1 is a large transmembrane...

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Detalles Bibliográficos
Autores principales:	Luna, Amalia, Segal-Eiras, Amada, Croce, María Virginia
Formato:	Articulo Revision
Lenguaje:	Inglés
Publicado:	2015
Materias:	Ciencias Médicas metastases cutaneous metastases breast cancer MUC1
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/127763 https://pmr.safisiol.org.ar/wp-content/uploads/2022/07/vol_8_3.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-127763
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Médicas metastases cutaneous metastases breast cancer MUC1
spellingShingle	Ciencias Médicas metastases cutaneous metastases breast cancer MUC1 Luna, Amalia Segal-Eiras, Amada Croce, María Virginia Metastatic dissemination with special emphasis on breast cancer cutaneous metastases
topic_facet	Ciencias Médicas metastases cutaneous metastases breast cancer MUC1
description	Metastatic development is a complex, multistage process involving modulation of cell phenotype, cell migration, and dynamic homeotypic as well as heterotypic cell-cell interactions. In breast cancer, MUC1 mucin has been emerging as a key molecule involved in metastasis. MUC1 is a large transmembrane glycoprotein expressed by mammary normal epithelial cells but it is overexpressed and underglycosylated in cancer cells. Cutaneous metastasis is a neoplastic lesion localized at the dermis or subcutaneous cellular tissue, which is not contiguous to the primary tumor, with an overall incidence of 5.3%. The most common tumor to metastasize to the skin is breast cancer with an incidence of 24%. We present a minireview on metastatic dissemination with special emphasis on breast cancer cutaneous metastases and the role that MUC1 plays on it.
format	Articulo Revision
author	Luna, Amalia Segal-Eiras, Amada Croce, María Virginia
author_facet	Luna, Amalia Segal-Eiras, Amada Croce, María Virginia
author_sort	Luna, Amalia
title	Metastatic dissemination with special emphasis on breast cancer cutaneous metastases
title_short	Metastatic dissemination with special emphasis on breast cancer cutaneous metastases
title_full	Metastatic dissemination with special emphasis on breast cancer cutaneous metastases
title_fullStr	Metastatic dissemination with special emphasis on breast cancer cutaneous metastases
title_full_unstemmed	Metastatic dissemination with special emphasis on breast cancer cutaneous metastases
title_sort	metastatic dissemination with special emphasis on breast cancer cutaneous metastases
publishDate	2015
url	http://sedici.unlp.edu.ar/handle/10915/127763 https://pmr.safisiol.org.ar/wp-content/uploads/2022/07/vol_8_3.pdf
work_keys_str_mv	AT lunaamalia metastaticdisseminationwithspecialemphasisonbreastcancercutaneousmetastases AT segaleirasamada metastaticdisseminationwithspecialemphasisonbreastcancercutaneousmetastases AT crocemariavirginia metastaticdisseminationwithspecialemphasisonbreastcancercutaneousmetastases
bdutipo_str	Repositorios
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Metastatic dissemination with special emphasis on breast cancer cutaneous metastases

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