Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)

In this work, the antifouling activity of five alkaloids, isolated from trees of the Atlantic rainforest, was studied. The tested alkaloids were olivacine (1), uleine (2) and N-methyltetrahydroellipticine (3) from Aspidosperma australe ('yellow guatambu') and the furoquinoline alkaloids ko...

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Autores principales: Pérez, Miriam Cristina, Pis Diez, Cristian M., Valdez, María Belén, García, Mónica Teresita, Paola, Analía C., Avigliano, Esteban, Palermo, Jorge Alejandro, Blustein, Guillermo
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2019
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/127053
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id I19-R120-10915-127053
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Ingeniería Forestal
Flindersiamine
Kokusaginine
N-methyltetrahydroellipticine
Antifouling
Indole alkaloids
spellingShingle Química
Ingeniería Forestal
Flindersiamine
Kokusaginine
N-methyltetrahydroellipticine
Antifouling
Indole alkaloids
Pérez, Miriam Cristina
Pis Diez, Cristian M.
Valdez, María Belén
García, Mónica Teresita
Paola, Analía C.
Avigliano, Esteban
Palermo, Jorge Alejandro
Blustein, Guillermo
Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)
topic_facet Química
Ingeniería Forestal
Flindersiamine
Kokusaginine
N-methyltetrahydroellipticine
Antifouling
Indole alkaloids
description In this work, the antifouling activity of five alkaloids, isolated from trees of the Atlantic rainforest, was studied. The tested alkaloids were olivacine (1), uleine (2) and N-methyltetrahydroellipticine (3) from Aspidosperma australe ('yellow guatambu') and the furoquinoline alkaloids kokusaginine (4) and flindersiamine (5) from Balfourodendron riedelianum ('white guatambu'). All these compounds can be isolated from their natural sources in high yields in a sustainable way. The five compounds were subjected to laboratory tests (attachment test of the mussel Mytilus edulis platensis) and field trials, by incorporation into soluble matrix paints, and 45 days of exposure of the painted panels in the sea. The results show that compound 3 is a very potent antifoulant, and that compounds 4 and 5 are also very active, while compounds 1 and 2 did not show any significant antifouling activity. These results open the way for the development of environmentally friendly antifouling agents, based on abundant and easy-to-purify compounds that can be obtained in a sustainable way.
format Articulo
Preprint
author Pérez, Miriam Cristina
Pis Diez, Cristian M.
Valdez, María Belén
García, Mónica Teresita
Paola, Analía C.
Avigliano, Esteban
Palermo, Jorge Alejandro
Blustein, Guillermo
author_facet Pérez, Miriam Cristina
Pis Diez, Cristian M.
Valdez, María Belén
García, Mónica Teresita
Paola, Analía C.
Avigliano, Esteban
Palermo, Jorge Alejandro
Blustein, Guillermo
author_sort Pérez, Miriam Cristina
title Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)
title_short Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)
title_full Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)
title_fullStr Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)
title_full_unstemmed Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "Guatambú" trees (Aspidosperma australe and Balfourodendron riedelianum)
title_sort isolation and antimacrofouling activity of indole and furoquinoline alkaloids from "guatambú" trees (aspidosperma australe and balfourodendron riedelianum)
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/127053
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