Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide
In recent decades the renin-angiotensin system has been established itself as a complex regulatory mechanism composed of different pathways involved in the control of physiological functions and, when for long term inappropriately activated, it is involved in the pathophysiology of different disease...
Guardado en:
| Autores principales: | , , , |
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| Formato: | Articulo Revision |
| Lenguaje: | Inglés |
| Publicado: |
2019
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/126797 https://pmr.safisiol.org.ar/archive/id/115 |
| Aporte de: |
| id |
I19-R120-10915-126797 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Ciencias Médicas Renin-angiotensin system Angiotensin-(1-7) Mas receptor Inflammation Resolution Asthma Arthritis Sistema Renina-Angiotensina Receptor Mas Inflamación Asma Artritis |
| spellingShingle |
Ciencias Médicas Renin-angiotensin system Angiotensin-(1-7) Mas receptor Inflammation Resolution Asthma Arthritis Sistema Renina-Angiotensina Receptor Mas Inflamación Asma Artritis Campagnole Santos, Maria Jose Magalhaes, Giselle S. Rodrigues Machado, Maria Gloria Santos, Robson A. S. Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| topic_facet |
Ciencias Médicas Renin-angiotensin system Angiotensin-(1-7) Mas receptor Inflammation Resolution Asthma Arthritis Sistema Renina-Angiotensina Receptor Mas Inflamación Asma Artritis |
| description |
In recent decades the renin-angiotensin system has been established itself as a complex regulatory mechanism composed of different pathways involved in the control of physiological functions and, when for long term inappropriately activated, it is involved in the pathophysiology of different diseases. Among its biologically active peptides, angiotensin-(1-7) and its receptor Mas, represent an important counter-regulatory mechanism due to their antihypertensive, anti-inflammatory, anti-proliferative and antifibrotic effects. In this review, we present data that besides demonstrating the antiinflammatory effect, indicate that angiotensin-(1-7) has a crucial additional effect on the return to tissue homeostasis, that is to promote resolution of the inflammatory process. These studies point angiotensin-(1-7) or activation of Mas receptor as important therapeutic targets for the treatment of inflammatory diseases. |
| format |
Articulo Revision |
| author |
Campagnole Santos, Maria Jose Magalhaes, Giselle S. Rodrigues Machado, Maria Gloria Santos, Robson A. S. |
| author_facet |
Campagnole Santos, Maria Jose Magalhaes, Giselle S. Rodrigues Machado, Maria Gloria Santos, Robson A. S. |
| author_sort |
Campagnole Santos, Maria Jose |
| title |
Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| title_short |
Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| title_full |
Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| title_fullStr |
Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| title_full_unstemmed |
Angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| title_sort |
angiotensin-(1-7): an anti-inflammatory and pro-resolutive peptide |
| publishDate |
2019 |
| url |
http://sedici.unlp.edu.ar/handle/10915/126797 https://pmr.safisiol.org.ar/archive/id/115 |
| work_keys_str_mv |
AT campagnolesantosmariajose angiotensin17anantiinflammatoryandproresolutivepeptide AT magalhaesgiselles angiotensin17anantiinflammatoryandproresolutivepeptide AT rodriguesmachadomariagloria angiotensin17anantiinflammatoryandproresolutivepeptide AT santosrobsonas angiotensin17anantiinflammatoryandproresolutivepeptide |
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Repositorios |
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1764820451211608064 |