Angiotensin-converting enzyme 2: angel or evil?

Angiotensin converting enzyme 2 (ACE2) is a key element of the protective arm of the reninangiotensin system (RAS). ACE2 acts to oppose the actions of angiotensin (Ang) II by generating Ang-(1–7) to reduce inflammation and fibrosis and mitigate end organ damage. ACE2 also acts as the receptor for se...

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Detalles Bibliográficos
Autor principal: Gironacci, Mariela M.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2021
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/126213
https://pmr.safisiol.org.ar/archive/id/127
Aporte de:
id I19-R120-10915-126213
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Angiotensin-converting enzyme 2
Angiotensin
COVID-19
Renin-angiotensin system
Enzima convertidora de angiotensina 2
Angiotensina
Sistema Renina-Angiotensina
spellingShingle Ciencias Médicas
Angiotensin-converting enzyme 2
Angiotensin
COVID-19
Renin-angiotensin system
Enzima convertidora de angiotensina 2
Angiotensina
Sistema Renina-Angiotensina
Gironacci, Mariela M.
Angiotensin-converting enzyme 2: angel or evil?
topic_facet Ciencias Médicas
Angiotensin-converting enzyme 2
Angiotensin
COVID-19
Renin-angiotensin system
Enzima convertidora de angiotensina 2
Angiotensina
Sistema Renina-Angiotensina
description Angiotensin converting enzyme 2 (ACE2) is a key element of the protective arm of the reninangiotensin system (RAS). ACE2 acts to oppose the actions of angiotensin (Ang) II by generating Ang-(1–7) to reduce inflammation and fibrosis and mitigate end organ damage. ACE2 also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2 to gain entry into human cells. SARS-CoV-2 is the etiological agent that causes coronavirus disease 2019 (COVID-19). The COVID-19 pandemic is associated with significant morbidity and mortality throughout the world, predominantly due to lung and cardiovascular injury. The present review is focused on ACE2, as a protective component of the RAS and as the receptor for SARS-CoV2.
format Articulo
Articulo
author Gironacci, Mariela M.
author_facet Gironacci, Mariela M.
author_sort Gironacci, Mariela M.
title Angiotensin-converting enzyme 2: angel or evil?
title_short Angiotensin-converting enzyme 2: angel or evil?
title_full Angiotensin-converting enzyme 2: angel or evil?
title_fullStr Angiotensin-converting enzyme 2: angel or evil?
title_full_unstemmed Angiotensin-converting enzyme 2: angel or evil?
title_sort angiotensin-converting enzyme 2: angel or evil?
publishDate 2021
url http://sedici.unlp.edu.ar/handle/10915/126213
https://pmr.safisiol.org.ar/archive/id/127
work_keys_str_mv AT gironaccimarielam angiotensinconvertingenzyme2angelorevil
bdutipo_str Repositorios
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