Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes

Pseudomonas aeruginosa is an opportunistic pathogen associated with a broad spectrum of infections in humans. However, the pathogenicity of environmental P. aeruginosa strains, especially isolates from museums and conservation laboratories, is not widely recognized. In this study, the virulence attr...

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Detalles Bibliográficos
Autores principales: Rajkowska, Katarzyna, Otlewska, Anna, Guiamet, Patricia Sandra, Wrzosek, Henryk, Machnowski, Waldemar
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Biología
Pseudomonas aeruginosa
Virulence
Occupational hazard
Archeological textile
SEM-EDX
FTIR
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/125390
https://www.mdpi.com/2076-3417/10/1/116
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-125390
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Biología
Pseudomonas aeruginosa
Virulence
Occupational hazard
Archeological textile
SEM-EDX
FTIR
spellingShingle Biología
Pseudomonas aeruginosa
Virulence
Occupational hazard
Archeological textile
SEM-EDX
FTIR
Rajkowska, Katarzyna
Otlewska, Anna
Guiamet, Patricia Sandra
Wrzosek, Henryk
Machnowski, Waldemar
Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes
topic_facet Biología
Pseudomonas aeruginosa
Virulence
Occupational hazard
Archeological textile
SEM-EDX
FTIR
description Pseudomonas aeruginosa is an opportunistic pathogen associated with a broad spectrum of infections in humans. However, the pathogenicity of environmental P. aeruginosa strains, especially isolates from museums and conservation laboratories, is not widely recognized. In this study, the virulence attributes of P. aeruginosa isolated from pre-Columbian textiles were compared to those of a clinical strain. Both genetically identified environmental strains (KP842564 and KP842565) exhibited a high ability to form biofilms on abiotic surfaces and high hemolytic activity. In addition, strain KP842564 was a moderate pyocyanin producer and showed proteolytic properties toward bovine serum albumin, fibrinogen, mucin, and casein. In contrast to the clinical isolate, the environmental strains were susceptible to all the tested antimicrobial agents. The strains also showed high bioadhesion and colonization capacity on archeological textile samples, in which wool fibers were the only source of nutrients, as confirmed by scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) analysis. This study highlights the need to identify microorganisms which inhabit historic objects, in order to avoid exposure to occupational hazards. Although the strain KP842565 exhibited only some of the examined virulence-related features, given that the production of pyocyanin and hemolysins as well as the formation of biofilm are important virulence factors of P. aeruginosa, the results indicate that these strains may present a potential health risk for humans.
format Articulo
Articulo
author Rajkowska, Katarzyna
Otlewska, Anna
Guiamet, Patricia Sandra
Wrzosek, Henryk
Machnowski, Waldemar
author_facet Rajkowska, Katarzyna
Otlewska, Anna
Guiamet, Patricia Sandra
Wrzosek, Henryk
Machnowski, Waldemar
author_sort Rajkowska, Katarzyna
title Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes
title_short Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes
title_full Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes
title_fullStr Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes
title_full_unstemmed Pre-Columbian Archeological Textiles: A Source of Pseudomonas aeruginosa with Virulence Attributes
title_sort pre-columbian archeological textiles: a source of pseudomonas aeruginosa with virulence attributes
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/125390
https://www.mdpi.com/2076-3417/10/1/116
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