Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids

Core-brush hybrid nanoparticles containing PEG surface functions are highly interesting as biologically inert and smart stimuli-responsive materials for future applications in biosensors, drug delivery, tissue engineering and optical systems. In this context, surface modification methodologies are c...

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Detalles Bibliográficos
Autores principales:	Penelas, María Jazmín, Contreras, Cintia Belén, Giussi, Juan Martín, Wolosiuk, Alejandro, Azzaroni, Omar, Avila Arturo Soler Illia, Galo Juan de
Formato:	Articulo Preprint
Lenguaje:	Inglés
Publicado:	2019
Materias:	Ciencias Exactas hybrid materials core-brush nanoparticles responsive silica colloids functional polymer brushes PEG-functionalized colloids
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/125180
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-125180
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Exactas hybrid materials core-brush nanoparticles responsive silica colloids functional polymer brushes PEG-functionalized colloids
spellingShingle	Ciencias Exactas hybrid materials core-brush nanoparticles responsive silica colloids functional polymer brushes PEG-functionalized colloids Penelas, María Jazmín Contreras, Cintia Belén Giussi, Juan Martín Wolosiuk, Alejandro Azzaroni, Omar Avila Arturo Soler Illia, Galo Juan de Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
topic_facet	Ciencias Exactas hybrid materials core-brush nanoparticles responsive silica colloids functional polymer brushes PEG-functionalized colloids
description	Core-brush hybrid nanoparticles containing PEG surface functions are highly interesting as biologically inert and smart stimuli-responsive materials for future applications in biosensors, drug delivery, tissue engineering and optical systems. In this context, surface modification methodologies are critical to exert a thorough control of morphological and functional aspects such as grafting density, polymer conformation or colloidal dispersability. In this work, we present core-brush hybrid nanoparticles synthesis from SiO₂ particles and an oligo(ethyleneglycol)-based polymer. Di(ethylene glycol) methyl ether methacrylate (DEGMA) was successfully grafted using the grafting-from approach. In particular, we compared DEGMA grafting on SiO₂ particles using three pathways, where route 1 and 2 corresponds to a surface-initiated atom radical polymerization (SI-ATRP), while pathway 3 consists in a photo-grafting polymerization. The polymer density grafted on the SiO₂ surface, as well as the dispersion and stability of the core-brush particles colloid system were investigated. We demonstrate that although all the methodologies were successful in immobilizing the PDEGMA on the surface, selection of the synthetic route is key to control crucial characteristics of core-brush NPs such as grafted polymer density, dispersion and colloidal stability. The accurate control of these critical features through the synthesis pathway is of great importance for the performance of these novel materials.
format	Articulo Preprint
author	Penelas, María Jazmín Contreras, Cintia Belén Giussi, Juan Martín Wolosiuk, Alejandro Azzaroni, Omar Avila Arturo Soler Illia, Galo Juan de
author_facet	Penelas, María Jazmín Contreras, Cintia Belén Giussi, Juan Martín Wolosiuk, Alejandro Azzaroni, Omar Avila Arturo Soler Illia, Galo Juan de
author_sort	Penelas, María Jazmín
title	Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
title_short	Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
title_full	Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
title_fullStr	Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
title_full_unstemmed	Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
title_sort	controlling dispersion, stability and polymer content on pdegma-functionalized core-brush silica colloids
publishDate	2019
url	http://sedici.unlp.edu.ar/handle/10915/125180
work_keys_str_mv	AT penelasmariajazmin controllingdispersionstabilityandpolymercontentonpdegmafunctionalizedcorebrushsilicacolloids AT contrerascintiabelen controllingdispersionstabilityandpolymercontentonpdegmafunctionalizedcorebrushsilicacolloids AT giussijuanmartin controllingdispersionstabilityandpolymercontentonpdegmafunctionalizedcorebrushsilicacolloids AT wolosiukalejandro controllingdispersionstabilityandpolymercontentonpdegmafunctionalizedcorebrushsilicacolloids AT azzaroniomar controllingdispersionstabilityandpolymercontentonpdegmafunctionalizedcorebrushsilicacolloids AT avilaarturosolerilliagalojuande controllingdispersionstabilityandpolymercontentonpdegmafunctionalizedcorebrushsilicacolloids
bdutipo_str	Repositorios
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Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids

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