Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC

A chiral capillary monolithic column for enantiomer separation in capillary electrochromatography was prepared by coating cellulose tris(3,5-dimethylphenylcarbamate) on porous glycidyl methacrylate-co-ethylene dimethacrylate monolith in capillary format grafted with chains of [2(methacryloyloxy)ethy...

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Autores principales:	Echevarría, Romina Noel, Carrasco Correa, Enrique Javier, Keunchkarian, Sonia, Reta, Mario Roberto, Herrero Martínez, José Manuel
Formato:	Articulo Preprint
Lenguaje:	Inglés
Publicado:	2018
Materias:	Química Monolithic hplc column Monolith Monomer Chemistry Acetonitrile Photografting Cellulose Capillary electrochromatography Chromatography Enantiomer Cellulose tris(3,5-dimethylphenylcarbamate) Chiral monolithic organic columns Enantioseparation
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/125064
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-125064
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Química Monolithic hplc column Monolith Monomer Chemistry Acetonitrile Photografting Cellulose Capillary electrochromatography Chromatography Enantiomer Cellulose tris(3,5-dimethylphenylcarbamate) Chiral monolithic organic columns Enantioseparation
spellingShingle	Química Monolithic hplc column Monolith Monomer Chemistry Acetonitrile Photografting Cellulose Capillary electrochromatography Chromatography Enantiomer Cellulose tris(3,5-dimethylphenylcarbamate) Chiral monolithic organic columns Enantioseparation Echevarría, Romina Noel Carrasco Correa, Enrique Javier Keunchkarian, Sonia Reta, Mario Roberto Herrero Martínez, José Manuel Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC
topic_facet	Química Monolithic hplc column Monolith Monomer Chemistry Acetonitrile Photografting Cellulose Capillary electrochromatography Chromatography Enantiomer Cellulose tris(3,5-dimethylphenylcarbamate) Chiral monolithic organic columns Enantioseparation
description	A chiral capillary monolithic column for enantiomer separation in capillary electrochromatography was prepared by coating cellulose tris(3,5-dimethylphenylcarbamate) on porous glycidyl methacrylate-co-ethylene dimethacrylate monolith in capillary format grafted with chains of [2(methacryloyloxy)ethyl] trimethylammonium chloride. The surface modification of the monolith by the photografting of [2(methacryloyloxy)ethyl] trimethylammonium chloride monomer as well as the coating conditions of cellulose tris(3,5-dimethylphenylcarbamate) onto the grafted monolithic scaffold were optimized to obtain a stable and reproducible chiral stationary phase for capillary electrochromatography. The effect of organic modifier (acetonitrile) in aqueous mobile phase for the enantiomer separation by capillary electrochromatography was also investigated. Several pairs of enantiomers including acidic, neutral, and basic analytes were tested and most of them were partially or completely resolved under aqueous mobile phases. The prepared monolithic chiral stationary phases exhibited a good stability, repeatability, and column-to-column reproducibility, with relative standard deviations below 11% in the studied electrochromatographic parameters.
format	Articulo Preprint
author	Echevarría, Romina Noel Carrasco Correa, Enrique Javier Keunchkarian, Sonia Reta, Mario Roberto Herrero Martínez, José Manuel
author_facet	Echevarría, Romina Noel Carrasco Correa, Enrique Javier Keunchkarian, Sonia Reta, Mario Roberto Herrero Martínez, José Manuel
author_sort	Echevarría, Romina Noel
title	Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC
title_short	Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC
title_full	Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC
title_fullStr	Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC
title_full_unstemmed	Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC
title_sort	photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in cec
publishDate	2018
url	http://sedici.unlp.edu.ar/handle/10915/125064
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bdutipo_str	Repositorios
_version_	1764820449950171138

Photografted methacrylate-based monolithic columns coated with cellulose tris(3,5-dimethylphenylcarbamate) for chiral separation in CEC

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