Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws

This work revisits the dynamic behaviour of stirred continuous reactors in which a single bioreaction with unknown kinetics occurs. Conditions on the feeding strategy to avoid washing out the biomass and falling in batch operation are obtained. These conditions derive in a closed positively invarian...

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Autores principales: De Battista, Hernán, Jamilis Ricaldoni, Martín Ignacio, Garelli, Fabricio, Picó, Jesús
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2018
Materias:
Ingeniería
Bioprocess control
Nonlinear control
Invariant control
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/124891
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-124891
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ingeniería
Bioprocess control
Nonlinear control
Invariant control
spellingShingle Ingeniería
Bioprocess control
Nonlinear control
Invariant control
De Battista, Hernán
Jamilis Ricaldoni, Martín Ignacio
Garelli, Fabricio
Picó, Jesús
Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
topic_facet Ingeniería
Bioprocess control
Nonlinear control
Invariant control
description This work revisits the dynamic behaviour of stirred continuous reactors in which a single bioreaction with unknown kinetics occurs. Conditions on the feeding strategy to avoid washing out the biomass and falling in batch operation are obtained. These conditions derive in a closed positively invariant region including the desired operating point. It is stated that no closed orbits may exist in this region and, furthermore, that no fixed point exists but on one of its borders. Therefore, global stability is achieved by finding a feeding law that fulfils the aforementioned invariant conditions and gives a single equilibrium for a first-order dynamics. These results are useful to determine the stability properties of different control laws and, more importantly, to design new ones. The main advantages of the proposed approach are its simplicity and that, differing from previous results, input saturation does not affect stability results. The potentiality of the developed tools is illustrated by means of classical and novel feeding laws.
format Articulo
Preprint
author De Battista, Hernán
Jamilis Ricaldoni, Martín Ignacio
Garelli, Fabricio
Picó, Jesús
author_facet De Battista, Hernán
Jamilis Ricaldoni, Martín Ignacio
Garelli, Fabricio
Picó, Jesús
author_sort De Battista, Hernán
title Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
title_short Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
title_full Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
title_fullStr Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
title_full_unstemmed Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
title_sort global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/124891
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AT garellifabricio globalstabilisationofcontinuousbioreactorstoolsforanalysisanddesignoffeedinglaws
AT picojesus globalstabilisationofcontinuousbioreactorstoolsforanalysisanddesignoffeedinglaws
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