Diabetes primary prevention program: new insights from data analysis of recruitment period

Background Primary Prevention of Diabetes Program in Buenos Aires Province evaluates the effectiveness of adopting healthy lifestyle to prevent type 2 diabetes (T2D) in people at high risk of developing it. We aimed to present preliminary data analysis of FINDRISC and laboratory measurements taken d...

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Autores principales: Gagliardino, Juan José, Elgart, Jorge Federico, Bourgeois, Marcelo Javier, Etchegoyen, Graciela Susana, Fantuzzi, Gabriel, Ré, Matías, Ricart, Juan Pablo Antonio, García, Silvia Mónica, Giampieri, Cecilia, González, Lorena, Suárez Crivaro, Florencia, Kronsbein, Peter, Angelini, Julieta María, Martínez, Camilo, Martínez, Jorge Alberto, Ricart, Alberto Omar, Spinedi, Eduardo Julio
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2018
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/124475
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id I19-R120-10915-124475
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Diabetes primary prevention
Pre-diabetes
Dyslipidemia in pre-diabetes
FINDRISC score
spellingShingle Ciencias Médicas
Diabetes primary prevention
Pre-diabetes
Dyslipidemia in pre-diabetes
FINDRISC score
Gagliardino, Juan José
Elgart, Jorge Federico
Bourgeois, Marcelo Javier
Etchegoyen, Graciela Susana
Fantuzzi, Gabriel
Ré, Matías
Ricart, Juan Pablo Antonio
García, Silvia Mónica
Giampieri, Cecilia
González, Lorena
Suárez Crivaro, Florencia
Kronsbein, Peter
Angelini, Julieta María
Martínez, Camilo
Martínez, Jorge Alberto
Ricart, Alberto Omar
Spinedi, Eduardo Julio
Diabetes primary prevention program: new insights from data analysis of recruitment period
topic_facet Ciencias Médicas
Diabetes primary prevention
Pre-diabetes
Dyslipidemia in pre-diabetes
FINDRISC score
description Background Primary Prevention of Diabetes Program in Buenos Aires Province evaluates the effectiveness of adopting healthy lifestyle to prevent type 2 diabetes (T2D) in people at high risk of developing it. We aimed to present preliminary data analysis of FINDRISC and laboratory measurements taken during recruitment of people for the Primary Prevention of Diabetes Program in Buenos Aires Province in the cities of La Plata, Berisso, and Ensenada, Argentina. Methods People were recruited through population approach (house-to-house survey by FINDRISC in randomized areas) and opportunistic approach (FINDRISC completed by participants during consultations for nonrelated prediabetes/diabetes symptoms in public and private primary care centres of cities involved). In people with FINDRISC score ≥ 13 points, we evaluated blood concentrations of HbA1c , creatinine, lipids, and an oral glucose tolerance test (OGTT). Results Approximately 3415 individuals completed the FINDRISC populational survey and 344 the opportunistic survey; 43% of the 2 groups scored over 13 points; 2.8 and 75.4% of them, respectively, took the prescribed OGTT. Approximately 53.7% of the OGTT showed normal values and 5.2% unknown T2D. The remaining cases showed 69.5% impaired fasting glucose, 13.6% impaired glucose tolerance, and 16.9% both impairments. HbA1c values showed significant differences compared with normal glucose tolerance (4.96 ± 0.43%), prediabetes (5.28 ± 0.51%), and T2D (5.60 ± 0.51%). Participants with prediabetes and T2D showed a predominant increase in low-density lipoprotein-cholesterol values. In prediabetes, >50% showed insulin resistance. Conclusions People with prediabetes/T2D had dyslipidemia associated with insulin resistance, which promotes the development of T2D and cardiovascular disease. Thus, it merits its appropriate treatment.
format Articulo
Preprint
author Gagliardino, Juan José
Elgart, Jorge Federico
Bourgeois, Marcelo Javier
Etchegoyen, Graciela Susana
Fantuzzi, Gabriel
Ré, Matías
Ricart, Juan Pablo Antonio
García, Silvia Mónica
Giampieri, Cecilia
González, Lorena
Suárez Crivaro, Florencia
Kronsbein, Peter
Angelini, Julieta María
Martínez, Camilo
Martínez, Jorge Alberto
Ricart, Alberto Omar
Spinedi, Eduardo Julio
author_facet Gagliardino, Juan José
Elgart, Jorge Federico
Bourgeois, Marcelo Javier
Etchegoyen, Graciela Susana
Fantuzzi, Gabriel
Ré, Matías
Ricart, Juan Pablo Antonio
García, Silvia Mónica
Giampieri, Cecilia
González, Lorena
Suárez Crivaro, Florencia
Kronsbein, Peter
Angelini, Julieta María
Martínez, Camilo
Martínez, Jorge Alberto
Ricart, Alberto Omar
Spinedi, Eduardo Julio
author_sort Gagliardino, Juan José
title Diabetes primary prevention program: new insights from data analysis of recruitment period
title_short Diabetes primary prevention program: new insights from data analysis of recruitment period
title_full Diabetes primary prevention program: new insights from data analysis of recruitment period
title_fullStr Diabetes primary prevention program: new insights from data analysis of recruitment period
title_full_unstemmed Diabetes primary prevention program: new insights from data analysis of recruitment period
title_sort diabetes primary prevention program: new insights from data analysis of recruitment period
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/124475
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