Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>

Glyphosate (GLY) is the most used herbicide worldwide and its effects on anurans are well known. Pollutants can cause physiological and morphological effects. Therefore, this study evaluated the effects of GLY on hepatic melanomacrophages as a response to environmental stressors. Three treatments we...

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Detalles Bibliográficos
Autores principales:	Pérez Iglesias, Juan Manuel, Franco Belussi, Lilian, Moreno, Liliana, Tripole, Susana, Oliveira, Classius de, Natale, Guillermo Sebastián
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2016
Materias:	Ciencias Exactas Glyphosate Melanomacrophages Melanin Hemosiderin Morphological responses Genotoxic effects
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/124026
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-124026
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Exactas Glyphosate Melanomacrophages Melanin Hemosiderin Morphological responses Genotoxic effects
spellingShingle	Ciencias Exactas Glyphosate Melanomacrophages Melanin Hemosiderin Morphological responses Genotoxic effects Pérez Iglesias, Juan Manuel Franco Belussi, Lilian Moreno, Liliana Tripole, Susana Oliveira, Classius de Natale, Guillermo Sebastián Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>
topic_facet	Ciencias Exactas Glyphosate Melanomacrophages Melanin Hemosiderin Morphological responses Genotoxic effects
description	Glyphosate (GLY) is the most used herbicide worldwide and its effects on anurans are well known. Pollutants can cause physiological and morphological effects. Therefore, this study evaluated the effects of GLY on hepatic melanomacrophages as a response to environmental stressors. Three treatments were exposed to different concentrations of pure GLY (100, 1000, and 10,000 μg g⁻¹, respectively), and there was also a control group. After the experimental time, liver and blood were analyzed. Melanomacrophages (MMCs) were located between the hepatocyte cordons, close to sinusoids. GLY increased the melanin area in MMCs of <i>Leptodactylus latinasus</i> exposed since lowest concentration until highest concentration. GLY also changed the occurrence of hepatic catabolism pigments into melanomacrophages and erythrocyte nuclear abnormalities; therefore, it can interfere with the hepatic metabolism. In conclusion, GLY promotes alterations in the hepatic tissue and erythrocyte nuclear abnormalities. Furthermore, MMCs may be useful as morphological responses of GLY effects.
format	Articulo Articulo
author	Pérez Iglesias, Juan Manuel Franco Belussi, Lilian Moreno, Liliana Tripole, Susana Oliveira, Classius de Natale, Guillermo Sebastián
author_facet	Pérez Iglesias, Juan Manuel Franco Belussi, Lilian Moreno, Liliana Tripole, Susana Oliveira, Classius de Natale, Guillermo Sebastián
author_sort	Pérez Iglesias, Juan Manuel
title	Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>
title_short	Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>
title_full	Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>
title_fullStr	Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>
title_full_unstemmed	Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>
title_sort	effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>leptodactylus latinasus</i>
publishDate	2016
url	http://sedici.unlp.edu.ar/handle/10915/124026
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Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran <i>Leptodactylus latinasus</i>

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