Impaired reproductive function in equines: from genetics to genomics

Fertility is one of the key factors in the economic and productive success of the equine industry. Despite this, studies on the genetic causes affecting reproductive performance are scarce, especially in mares, where the genetic architecture of the reproductive traits is extremely complex. Today, wi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Laseca, Nora, Anaya, G., Peña, Zahira, Pirosanto, Yamila, Molina, Antonio, Demyda Peyrás, Sebastián
Formato: Articulo
Lenguaje:Inglés
Publicado: 2021
Materias:
Zoología
Ciencias Veterinarias
Candidate genes
Copy number variations
Fertility
Genome-wide association studies
Genomics
Inbreeding
Mares
Reproductive traits
Stallions
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/123703
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-123703
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Zoología
Ciencias Veterinarias
Candidate genes
Copy number variations
Fertility
Genome-wide association studies
Genomics
Inbreeding
Mares
Reproductive traits
Stallions
spellingShingle Zoología
Ciencias Veterinarias
Candidate genes
Copy number variations
Fertility
Genome-wide association studies
Genomics
Inbreeding
Mares
Reproductive traits
Stallions
Laseca, Nora
Anaya, G.
Peña, Zahira
Pirosanto, Yamila
Molina, Antonio
Demyda Peyrás, Sebastián
Impaired reproductive function in equines: from genetics to genomics
topic_facet Zoología
Ciencias Veterinarias
Candidate genes
Copy number variations
Fertility
Genome-wide association studies
Genomics
Inbreeding
Mares
Reproductive traits
Stallions
description Fertility is one of the key factors in the economic and productive success of the equine industry. Despite this, studies on the genetic causes affecting reproductive performance are scarce, especially in mares, where the genetic architecture of the reproductive traits is extremely complex. Today, with the increasing availability of new genomic methodologies for this species, we are presented with an interesting opportunity to understand the genetic basis of equine reproductive disorders. These include, among others, novel techniques for detecting chromosomal abnormalities, whose association with infertility in horses was established over 50 years ago; new sequencing technologies permitting an accurate detection of point mutations influencing fertility, as well as the study of inbreeding and molecular homozygosity, which has been widely suggested as one of the main causes of low reproductive performance in horses. Finally, over the last few years, reproductive performance has also been associated with copy number variants and candidate genes detected by genome-wide association studies on fertility traits. However, such studies are still scarce, probably because they depend on the existence of large and accurate phenotypic datasets of reproductive and/or fertility traits, which are still difficult to obtain in equines.
format Articulo
Articulo
author Laseca, Nora
Anaya, G.
Peña, Zahira
Pirosanto, Yamila
Molina, Antonio
Demyda Peyrás, Sebastián
author_facet Laseca, Nora
Anaya, G.
Peña, Zahira
Pirosanto, Yamila
Molina, Antonio
Demyda Peyrás, Sebastián
author_sort Laseca, Nora
title Impaired reproductive function in equines: from genetics to genomics
title_short Impaired reproductive function in equines: from genetics to genomics
title_full Impaired reproductive function in equines: from genetics to genomics
title_fullStr Impaired reproductive function in equines: from genetics to genomics
title_full_unstemmed Impaired reproductive function in equines: from genetics to genomics
title_sort impaired reproductive function in equines: from genetics to genomics
publishDate 2021
url http://sedici.unlp.edu.ar/handle/10915/123703
work_keys_str_mv AT lasecanora impairedreproductivefunctioninequinesfromgeneticstogenomics
AT anayag impairedreproductivefunctioninequinesfromgeneticstogenomics
AT penazahira impairedreproductivefunctioninequinesfromgeneticstogenomics
AT pirosantoyamila impairedreproductivefunctioninequinesfromgeneticstogenomics
AT molinaantonio impairedreproductivefunctioninequinesfromgeneticstogenomics
AT demydapeyrassebastian impairedreproductivefunctioninequinesfromgeneticstogenomics
bdutipo_str Repositorios
_version_ 1764820450073903108

Ejemplares similares