The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide

Juvenile hormones (JHs) are sesquiterpenoids synthesized by the corpora allata (CA). They play critical roles during insect development and reproduction. The first JH was described in 1934 as a "metamorphosis inhibitory hormone" in Rhodnius prolixus by Sir Vincent B. Wigglesworth. Remarkab...

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Detalles Bibliográficos
Autores principales: Villalobos Sambucaro, María José, Nouzova, Marcela, Ramirez, Cesar E., Alzugaray, María Eugenia, Fernandez Lima, Francisco, Ronderos, Jorge Rafael, Noriega, Fernando G.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2020
Materias:
Ciencias Naturales
Rhodnius
Hormonas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/123402
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-123402
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Naturales
Rhodnius
Hormonas
spellingShingle Ciencias Naturales
Rhodnius
Hormonas
Villalobos Sambucaro, María José
Nouzova, Marcela
Ramirez, Cesar E.
Alzugaray, María Eugenia
Fernandez Lima, Francisco
Ronderos, Jorge Rafael
Noriega, Fernando G.
The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide
topic_facet Ciencias Naturales
Rhodnius
Hormonas
description Juvenile hormones (JHs) are sesquiterpenoids synthesized by the corpora allata (CA). They play critical roles during insect development and reproduction. The first JH was described in 1934 as a "metamorphosis inhibitory hormone" in Rhodnius prolixus by Sir Vincent B. Wigglesworth. Remarkably, in spite of the importance of R. prolixus as vectors of Chagas disease and model organisms in insect physiology, the original JH that Wigglesworth described for the kissing-bug R. prolixus remained unidentified. We employed liquid chromatography mass spectrometry to search for the JH homologs present in the hemolymph of fourth instar nymphs of R. prolixus. Wigglesworth's original JH is the JH III skipped bisepoxide (JHSB3), a homolog identified in other heteropteran species. Changes in the titer of JHSB3 were studied during the 10-day long molting cycle of 4th instar nymph, between a blood meal and the ecdysis to 5th instar. In addition we measured the changes of mRNA levels in the CA for the 13 enzymes of the JH biosynthetic pathway during the molting cycle of 4th instar. Almost 90 years after the first descriptions of the role of JH in insects, this study finally reveals that the specific JH homolog responsible for Wigglesworth's original observations is JHSB3.
format Articulo
Articulo
author Villalobos Sambucaro, María José
Nouzova, Marcela
Ramirez, Cesar E.
Alzugaray, María Eugenia
Fernandez Lima, Francisco
Ronderos, Jorge Rafael
Noriega, Fernando G.
author_facet Villalobos Sambucaro, María José
Nouzova, Marcela
Ramirez, Cesar E.
Alzugaray, María Eugenia
Fernandez Lima, Francisco
Ronderos, Jorge Rafael
Noriega, Fernando G.
author_sort Villalobos Sambucaro, María José
title The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide
title_short The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide
title_full The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide
title_fullStr The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide
title_full_unstemmed The juvenile hormone described in <i>Rhodnius prolixus</i> by Wigglesworth is juvenile hormone III skipped bisepoxide
title_sort juvenile hormone described in <i>rhodnius prolixus</i> by wigglesworth is juvenile hormone iii skipped bisepoxide
publishDate 2020
url http://sedici.unlp.edu.ar/handle/10915/123402
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