Consequences of smoking during pregnancy for mother and child

Objective: to evaluate the consequences of maternal smoking. Methods: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained...

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Autores principales: Marín, Gustavo Horacio, Delgado, Liliana, Sager, Gustavo, Visentín, Silvana Beatriz, Azzaro, Sebastiana, Tozzi, Mabel
Formato: Articulo
Lenguaje:Inglés
Publicado: 2003
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/123044
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id I19-R120-10915-123044
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Medicina
Pregnancy
Smoking
spellingShingle Medicina
Pregnancy
Smoking
Marín, Gustavo Horacio
Delgado, Liliana
Sager, Gustavo
Visentín, Silvana Beatriz
Azzaro, Sebastiana
Tozzi, Mabel
Consequences of smoking during pregnancy for mother and child
topic_facet Medicina
Pregnancy
Smoking
description Objective: to evaluate the consequences of maternal smoking. Methods: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained to determine blood elements and flow cytometry analysis of lymphocyte subsets performed. Data from smoking (S) and non-smoking (NS) groups were evaluated through relative risk, chi square and Student's t test. Results: of all patients, 887 were NS and 226 said they smoked over five-cigarettes/day (S). The S group showed a higher probability of premature deliveries when compared to the NS group, with newborns weighing under 2,5kg, small in relation to gestational age, with Apgar scores at the 5th minute under six and hyaline membrane syndrome; intrauterine death risk was higher in this group who attended less medical appointments than scheduled. Umbilical cord blood analysis indicated lower reticulocyte index for S mothers, neutrophil count and CD4/CD8 ratio and increased erythroblast, eosinophil, basophil, total and CD8+T lymphocyte counts. Conclusions: data could explain the observations by other authors related to an increased incidence of allergy and infections in newborns caused by maternal smoking.
format Articulo
Articulo
author Marín, Gustavo Horacio
Delgado, Liliana
Sager, Gustavo
Visentín, Silvana Beatriz
Azzaro, Sebastiana
Tozzi, Mabel
author_facet Marín, Gustavo Horacio
Delgado, Liliana
Sager, Gustavo
Visentín, Silvana Beatriz
Azzaro, Sebastiana
Tozzi, Mabel
author_sort Marín, Gustavo Horacio
title Consequences of smoking during pregnancy for mother and child
title_short Consequences of smoking during pregnancy for mother and child
title_full Consequences of smoking during pregnancy for mother and child
title_fullStr Consequences of smoking during pregnancy for mother and child
title_full_unstemmed Consequences of smoking during pregnancy for mother and child
title_sort consequences of smoking during pregnancy for mother and child
publishDate 2003
url http://sedici.unlp.edu.ar/handle/10915/123044
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