Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle

The bovine leukemia virus (BLV) is an exogenous retrovirus belonging to the Deltaretrovirus genus. This enveloped virus naturally infects B-lymphocytes causing enzootic bovine leukemia (EBL), which is spread worldwide, mainly in dairy cattle. The virus might produce cell-mediated immunity disorders,...

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Detalles Bibliográficos
Autores principales: Dolcini, Guillermina Laura, Ladera Gómez, Marla Eliana, Nieto Farias, María Victoria, Váter, Adrián Alejandro, Ceriani, María Carolina
Formato: Objeto de conferencia Resumen
Lenguaje:Inglés
Publicado: 2021
Materias:
Ciencias Veterinarias
BLV
Bovine cytokines
PBMC
Somatic cells
Milk
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/122506
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-122506
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
BLV
Bovine cytokines
PBMC
Somatic cells
Milk
spellingShingle Ciencias Veterinarias
BLV
Bovine cytokines
PBMC
Somatic cells
Milk
Dolcini, Guillermina Laura
Ladera Gómez, Marla Eliana
Nieto Farias, María Victoria
Váter, Adrián Alejandro
Ceriani, María Carolina
Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle
topic_facet Ciencias Veterinarias
BLV
Bovine cytokines
PBMC
Somatic cells
Milk
description The bovine leukemia virus (BLV) is an exogenous retrovirus belonging to the Deltaretrovirus genus. This enveloped virus naturally infects B-lymphocytes causing enzootic bovine leukemia (EBL), which is spread worldwide, mainly in dairy cattle. The virus might produce cell-mediated immunity disorders, which may lead to opportunistic infections in BLV-infected cattle. Thus, the performance of dairy cattle is impaired, leading to large economic losses in the dairy industry. A study was carried out to investigate the levels of proviral load as well as mRNA expression of cytokines in peripheral blood mononuclear cells (PBMC) and milk somatic cells (SC) of low proviral load (LPL), high proviral load (HPL) and uninfected cattle (controls). A total of 51 BLV- infected cows and 16 controls were included. The levels of proviral loadin PBMC and SC as well as the expression levels of cytokine mRNA between LPL and HPL cattle were measured by real-time PCR (qPCR).
format Objeto de conferencia
Resumen
author Dolcini, Guillermina Laura
Ladera Gómez, Marla Eliana
Nieto Farias, María Victoria
Váter, Adrián Alejandro
Ceriani, María Carolina
author_facet Dolcini, Guillermina Laura
Ladera Gómez, Marla Eliana
Nieto Farias, María Victoria
Váter, Adrián Alejandro
Ceriani, María Carolina
author_sort Dolcini, Guillermina Laura
title Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle
title_short Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle
title_full Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle
title_fullStr Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle
title_full_unstemmed Comparison of proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from BLV-infected cattle
title_sort comparison of proviral load levels and mrna expression of cytokines in peripheral blood mononuclear cells and milk somatic cells from blv-infected cattle
publishDate 2021
url http://sedici.unlp.edu.ar/handle/10915/122506
work_keys_str_mv AT dolciniguillerminalaura comparisonofproviralloadlevelsandmrnaexpressionofcytokinesinperipheralbloodmononuclearcellsandmilksomaticcellsfromblvinfectedcattle
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bdutipo_str Repositorios
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