Chromosomic breaks and gaps in breast carcinomas of female dog

A cytogenetic study of canine breast carcinomas was performed in order to identify the occurrence of chromosomal abnormalities. Samples of spontaneous canine mammary tumors were submitted for histopathological evaluation and for cytogenetic analysis. Hematoxylin and eosin staining was used for the...

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Autores principales: Canzoneri, Romina, Rosciani, A. S., Jorge, L.C.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Ciencias Veterinarias
Dog
Mammary tumors
Cytogenetic
Fragile sites
Perra
Tumores mamarios
Citogenética
Sitios frágiles
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/116105
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-116105
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Dog
Mammary tumors
Cytogenetic
Fragile sites
Perra
Tumores mamarios
Citogenética
Sitios frágiles
spellingShingle Ciencias Veterinarias
Dog
Mammary tumors
Cytogenetic
Fragile sites
Perra
Tumores mamarios
Citogenética
Sitios frágiles
Canzoneri, Romina
Rosciani, A. S.
Jorge, L.C.
Chromosomic breaks and gaps in breast carcinomas of female dog
topic_facet Ciencias Veterinarias
Dog
Mammary tumors
Cytogenetic
Fragile sites
Perra
Tumores mamarios
Citogenética
Sitios frágiles
description A cytogenetic study of canine breast carcinomas was performed in order to identify the occurrence of chromosomal abnormalities. Samples of spontaneous canine mammary tumors were submitted for histopathological evaluation and for cytogenetic analysis. Hematoxylin and eosin staining was used for the former and conventional Giemsa staining and NOR banding were performed for the latter. Chromosomal breaks and/or gaps affecting autosomes and sex chromosomes were seen in 5 of a total of 14 cases. The percentage of metaphases with abnormal chromosomes was 61%, the average number of metaphase`s chromosomes affected was 1.26, while a media of 1.47 breaks and/or gaps was seen per metaphase. These alterations were observed in complex and simple carcinomas. We propose to include this type of cytogenetic study in addition to routine techniques in order to improve the diagnosis and prognosis prediction.
format Articulo
Articulo
author Canzoneri, Romina
Rosciani, A. S.
Jorge, L.C.
author_facet Canzoneri, Romina
Rosciani, A. S.
Jorge, L.C.
author_sort Canzoneri, Romina
title Chromosomic breaks and gaps in breast carcinomas of female dog
title_short Chromosomic breaks and gaps in breast carcinomas of female dog
title_full Chromosomic breaks and gaps in breast carcinomas of female dog
title_fullStr Chromosomic breaks and gaps in breast carcinomas of female dog
title_full_unstemmed Chromosomic breaks and gaps in breast carcinomas of female dog
title_sort chromosomic breaks and gaps in breast carcinomas of female dog
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/116105
work_keys_str_mv AT canzoneriromina chromosomicbreaksandgapsinbreastcarcinomasoffemaledog
AT roscianias chromosomicbreaksandgapsinbreastcarcinomasoffemaledog
AT jorgelc chromosomicbreaksandgapsinbreastcarcinomasoffemaledog
AT canzoneriromina quiebresygapscromosomicosencarcinomasmamariosdehembrascaninas
AT roscianias quiebresygapscromosomicosencarcinomasmamariosdehembrascaninas
AT jorgelc quiebresygapscromosomicosencarcinomasmamariosdehembrascaninas
bdutipo_str Repositorios
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