Toxocara canis: migración larval y eosinofilia en el hospedador paraténico

The objective of this study was to analize the migratory behaviour of larvae of Toxocara canis related to eosinophilia in paratenic hosts. Mice were used as experimental models. In rodents and humans the migratory route and the pathogenesis of the parasite are similar. Balb/c mice were inoculated in...

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Detalles Bibliográficos
Autores principales: Guardis, Mónica del Valle, Radman, Nilda Ester, Burgos, Lola, Fonrouge, Reinaldo Domingo, Archelli, Susana Mónica
Formato: Articulo
Lenguaje:Español
Publicado: 2002
Materias:
Ciencias Veterinarias
Toxocara canis
Eosinophilia
Experimental model
Paratenic host
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/109495
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-109495
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Español
topic Ciencias Veterinarias
Toxocara canis
Eosinophilia
Experimental model
Paratenic host
spellingShingle Ciencias Veterinarias
Toxocara canis
Eosinophilia
Experimental model
Paratenic host
Guardis, Mónica del Valle
Radman, Nilda Ester
Burgos, Lola
Fonrouge, Reinaldo Domingo
Archelli, Susana Mónica
Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
topic_facet Ciencias Veterinarias
Toxocara canis
Eosinophilia
Experimental model
Paratenic host
description The objective of this study was to analize the migratory behaviour of larvae of Toxocara canis related to eosinophilia in paratenic hosts. Mice were used as experimental models. In rodents and humans the migratory route and the pathogenesis of the parasite are similar. Balb/c mice were inoculated intragastrically with 250 (± 10) embryonated eggs. Larvae recovery: eyes and encephalon were chosen as reference organs. In the encephalon and the eye, larval recovery began in the forth and twelfth day post-inoculation respectively. The association measured by the correlation coefficient between time of observation and recovered larvae in each organ was: right eye (RE) r= 0.24; left eye (LE) r= 0.43; encephalon (E) r= 0.60. The recovery of inoculated larvae is significantly higher in the encephalon than in the eyeballs (Chi square: 185; p < 0.00001), in 80 % of mice eosinophils exceeded 6% of the formula. The correlation between eosinophilia and larval recovery in the organs observed was: 0.33 for the right eye (RE); 0.21 for the left eye (LE) and 0.44 for the encephalon; these correlation values are considered low, suggesting no association between eosinophilia and the quantity of T. canis larvae lodged in the eyes (ocular toxocarosis) or in the encephalon (cerebrospinal toxocarosis).
format Articulo
Articulo
author Guardis, Mónica del Valle
Radman, Nilda Ester
Burgos, Lola
Fonrouge, Reinaldo Domingo
Archelli, Susana Mónica
author_facet Guardis, Mónica del Valle
Radman, Nilda Ester
Burgos, Lola
Fonrouge, Reinaldo Domingo
Archelli, Susana Mónica
author_sort Guardis, Mónica del Valle
title Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_short Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_full Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_fullStr Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_full_unstemmed Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_sort toxocara canis: migración larval y eosinofilia en el hospedador paraténico
publishDate 2002
url http://sedici.unlp.edu.ar/handle/10915/109495
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