Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays

Data set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Suárez, Santiago E., Aphalo, Paula, Rinaldi, Gustavo, Quiroga, Alejandra Viviana, Añón, María Cristina
Formato: Conjunto de datos
Lenguaje:Inglés
Publicado: 2020
Materias:
Bioquímica
https://purl.org/becyt/ford/1.6
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/107694
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7011023&blobtype=pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-107694
record_format dspace
spelling I19-R120-10915-1076942023-04-27T15:09:32Z http://sedici.unlp.edu.ar/handle/10915/107694 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7011023&blobtype=pdf Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays Suárez, Santiago E. Aphalo, Paula Rinaldi, Gustavo Quiroga, Alejandra Viviana Añón, María Cristina 2020-10-26T15:54:15Z 2020-04 en Bioquímica https://purl.org/becyt/ford/1.6 Amaranth proteins Protein hydrolysates Bioactive peptides Renin-angiotensin system Antihypertensive emulsions Spontaneously hypertensive rats Data set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR) of different samples with amaranth proteins/peptides. The effect of these samples on RAS system was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. In addition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experiments were done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/ peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensive individuals. Fil: Añón, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina. Fil: Aphalo, Paula. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina. Fil: Quiroga, Alejandra Viviana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos;Argentina Fil: Quiroga, Alejandra Viviana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina Fil: Rinaldi, Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina Fil: Suárez, Santiago E.. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina Fil: Suárez, Santiago E.. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina Centro de Investigación y Desarrollo en Criotecnología de Alimentos Facultad de Ciencias Médicas Conjunto de datos Conjunto de datos http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) application/pdf
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Bioquímica
https://purl.org/becyt/ford/1.6
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
spellingShingle Bioquímica
https://purl.org/becyt/ford/1.6
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
Suárez, Santiago E.
Aphalo, Paula
Rinaldi, Gustavo
Quiroga, Alejandra Viviana
Añón, María Cristina
Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
topic_facet Bioquímica
https://purl.org/becyt/ford/1.6
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
description Data set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR) of different samples with amaranth proteins/peptides. The effect of these samples on RAS system was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. In addition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experiments were done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/ peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensive individuals.
format Conjunto de datos
Conjunto de datos
author Suárez, Santiago E.
Aphalo, Paula
Rinaldi, Gustavo
Quiroga, Alejandra Viviana
Añón, María Cristina
author_facet Suárez, Santiago E.
Aphalo, Paula
Rinaldi, Gustavo
Quiroga, Alejandra Viviana
Añón, María Cristina
author_sort Suárez, Santiago E.
title Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_short Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_full Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_fullStr Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_full_unstemmed Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_sort data set on effect of amaranth proteins on the ras system: in vitro, in vivo and ex vivo assays
publishDate 2020
url http://sedici.unlp.edu.ar/handle/10915/107694
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7011023&blobtype=pdf
work_keys_str_mv AT suarezsantiagoe datasetoneffectofamaranthproteinsontherassysteminvitroinvivoandexvivoassays
AT aphalopaula datasetoneffectofamaranthproteinsontherassysteminvitroinvivoandexvivoassays
AT rinaldigustavo datasetoneffectofamaranthproteinsontherassysteminvitroinvivoandexvivoassays
AT quirogaalejandraviviana datasetoneffectofamaranthproteinsontherassysteminvitroinvivoandexvivoassays
AT anonmariacristina datasetoneffectofamaranthproteinsontherassysteminvitroinvivoandexvivoassays
_version_ 1765659800740298752

Ejemplares similares