Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay

Sarcocystis spp. are causative agents of bovine eosinophilic myositis and/or myocarditis, which are chronic subclinical myopathies that are occasionally responsible for condemnation at slaughterhouses. Sarcocystis cruzi is a protozoan parasite of worldwide distribution transmitted by canids, most co...

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Detalles Bibliográficos
Autores principales:	Aráoz, Virginia, Silva Silveira, Caroline da, Moré, Gastón Andrés, Banchero, Georgget, Riet Correa, Franklin, Giannitti, Federico
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2019
Materias:	Ciencias Veterinarias cattle eosinophilic myocarditis fatality Sarcocystis cruzi sarcocystosis
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/107512 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6857021&blobtype=pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-107512
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Veterinarias cattle eosinophilic myocarditis fatality Sarcocystis cruzi sarcocystosis
spellingShingle	Ciencias Veterinarias cattle eosinophilic myocarditis fatality Sarcocystis cruzi sarcocystosis Aráoz, Virginia Silva Silveira, Caroline da Moré, Gastón Andrés Banchero, Georgget Riet Correa, Franklin Giannitti, Federico Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay
topic_facet	Ciencias Veterinarias cattle eosinophilic myocarditis fatality Sarcocystis cruzi sarcocystosis
description	Sarcocystis spp. are causative agents of bovine eosinophilic myositis and/or myocarditis, which are chronic subclinical myopathies that are occasionally responsible for condemnation at slaughterhouses. Sarcocystis cruzi is a protozoan parasite of worldwide distribution transmitted by canids, most commonly associated with subclinical infection in cattle. Although S. cruzi infections can rarely lead to fatal systemic disease, fatal cardiac cases with confirmation of the etiologic diagnosis have not been reported, to our knowledge. We describe herein an unusual case of S. cruzi–induced fatal bovine eosinophilic myocarditis. A 22-mo-old, Holstein–Hereford heifer, in a group of 110 cattle on pasture, manifested growth retardation and died in February 2017. Autopsy revealed myriad yellow-green 1–3-mm coalescing foci, surrounded by fibrosis, affecting ~75% of the ventricular myocardium. Pulmonary edema, ascites, and hydrothorax were consistent with chronic congestive heart failure. Histology revealed severe eosinophilic, granulomatous, necrotizing myocarditis, with multinucleate giant cells, fibrosis, and mineralization. Numerous thin-walled protozoan cysts resembling Sarcocystis spp. were present in the necrotic foci and within the sarcoplasm of adjacent cardiomyocytes. PCR and sequencing of the 18S rRNA gene revealed 99.9–100% homology with S. cruzi. Sarcocystosis can be a rare cause of fatal myocarditis in cattle.
format	Articulo Comunicacion
author	Aráoz, Virginia Silva Silveira, Caroline da Moré, Gastón Andrés Banchero, Georgget Riet Correa, Franklin Giannitti, Federico
author_facet	Aráoz, Virginia Silva Silveira, Caroline da Moré, Gastón Andrés Banchero, Georgget Riet Correa, Franklin Giannitti, Federico
author_sort	Aráoz, Virginia
title	Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay
title_short	Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay
title_full	Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay
title_fullStr	Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay
title_full_unstemmed	Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay
title_sort	fatal <i>sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in uruguay
publishDate	2019
url	http://sedici.unlp.edu.ar/handle/10915/107512 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6857021&blobtype=pdf
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bdutipo_str	Repositorios
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Fatal <i>Sarcocystis cruzi</i>-induced eosinophilic myocarditis in a heifer in Uruguay

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