Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity
Celiac disease (CD) affects a growing number of individuals worldwide. To elucidate the causes for this increase, future multidisciplinary collaboration is key to understanding the interactions between immunoreactive components in gluten-containing cereals and the human gastrointestinal tract and im...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2020
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/107438 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7090026&blobtype=pdf |
| Aporte de: |
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I19-R120-10915-107438 |
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dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Biología Ciencias Médicas Barley Celiac disease Gluten Gluten-free diet Prolamin working group Rye Wheat |
| spellingShingle |
Biología Ciencias Médicas Barley Celiac disease Gluten Gluten-free diet Prolamin working group Rye Wheat Scherf, Katharina A Catassi, Carlo Chirdo, Fernando Gabriel Ciclitira, Paul J. Feighery, Conleth Gianfrani, Carmen Koning, Frits Lundin, Knut E. A. Schuppan, Detlef Smulders, Marinus J. M. Tranquet, Olivier Troncone, Riccardo Koehler, Peter Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity |
| topic_facet |
Biología Ciencias Médicas Barley Celiac disease Gluten Gluten-free diet Prolamin working group Rye Wheat |
| description |
Celiac disease (CD) affects a growing number of individuals worldwide. To elucidate the causes for this increase, future multidisciplinary collaboration is key to understanding the interactions between immunoreactive components in gluten-containing cereals and the human gastrointestinal tract and immune system and to devise strategies for CD prevention and treatment beyond the gluten-free diet. During the last meetings, the Working Group on Prolamin Analysis and Toxicity (Prolamin Working Group, PWG) discussed recent progress in the field together with key stakeholders from celiac disease societies, academia, industry and regulatory bodies. Based on the current state of knowledge, this perspective from the PWG members provides recommendations regarding clinical, analytical and legal aspects of CD. The selected key topics that require future multidisciplinary collaborative efforts in the clinical field are to collect robust data on the increasing prevalence of CD, to evaluate what is special about gluten-specific T cells, to study their kinetics and transcriptomics and to put some attention to the identification of the environmental agents that facilitate the breaking of tolerance to gluten. In the field of gluten analysis, the key topics are the precise assessment of gluten immunoreactive components in wheat, rye and barley to understand how these are affected by genetic and environmental factors, the comparison of different methods for compliance monitoring of gluten-free products and the development of improved reference materials for gluten analysis. |
| format |
Articulo Articulo |
| author |
Scherf, Katharina A Catassi, Carlo Chirdo, Fernando Gabriel Ciclitira, Paul J. Feighery, Conleth Gianfrani, Carmen Koning, Frits Lundin, Knut E. A. Schuppan, Detlef Smulders, Marinus J. M. Tranquet, Olivier Troncone, Riccardo Koehler, Peter |
| author_facet |
Scherf, Katharina A Catassi, Carlo Chirdo, Fernando Gabriel Ciclitira, Paul J. Feighery, Conleth Gianfrani, Carmen Koning, Frits Lundin, Knut E. A. Schuppan, Detlef Smulders, Marinus J. M. Tranquet, Olivier Troncone, Riccardo Koehler, Peter |
| author_sort |
Scherf, Katharina A |
| title |
Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity |
| title_short |
Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity |
| title_full |
Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity |
| title_fullStr |
Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity |
| title_full_unstemmed |
Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity |
| title_sort |
recent progress and recommendations on celiac disease from the working group on prolamin analysis and toxicity |
| publishDate |
2020 |
| url |
http://sedici.unlp.edu.ar/handle/10915/107438 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7090026&blobtype=pdf |
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