Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina

Porcine parvovirus (PPV) is one of many pathogens responsible for reproductive failure in pregnant sows. Several studies have reported the appearance of new PPV strains that differ from previous isolates both genetically and antigenically. Thus, the protective effects of commercially inactivated vac...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Serena, María Soledad, Cappuccio, Javier Alejandro, Metz, Germán Ernesto, Aspitia, Carolina Gabriela, Dibárbora, M., Gallo Calderón, M., Echeverría, María Gabriela
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Ciencias Veterinarias
Biotechnology
Immunology
Microbiology
Molecular biology
Veterinary medicine
Porcine parvovirus
Reproductive failures
Molecular characterization
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/107349
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6881615&blobtype=pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-107349
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Biotechnology
Immunology
Microbiology
Molecular biology
Veterinary medicine
Porcine parvovirus
Reproductive failures
Molecular characterization
spellingShingle Ciencias Veterinarias
Biotechnology
Immunology
Microbiology
Molecular biology
Veterinary medicine
Porcine parvovirus
Reproductive failures
Molecular characterization
Serena, María Soledad
Cappuccio, Javier Alejandro
Metz, Germán Ernesto
Aspitia, Carolina Gabriela
Dibárbora, M.
Gallo Calderón, M.
Echeverría, María Gabriela
Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina
topic_facet Ciencias Veterinarias
Biotechnology
Immunology
Microbiology
Molecular biology
Veterinary medicine
Porcine parvovirus
Reproductive failures
Molecular characterization
description Porcine parvovirus (PPV) is one of many pathogens responsible for reproductive failure in pregnant sows. Several studies have reported the appearance of new PPV strains that differ from previous isolates both genetically and antigenically. Thus, the protective effects of commercially inactivated vaccines could not be complete. In South America, the information about PPV is limited. Thus, the aim of the present study was to detect and characterize the PPV strains present in 131 mummies or stillbirths from normal deliveries in sows from a commercial swine farm of Argentina that uses the commercial vaccine. PCR results showed that 17/131 were positive to PPV. Ten of these viruses were isolated and sequenced. All viruses were related to the PPV1 sequence (NADL-2), maintaining the amino acid differences in positions 436 (S–P) and 565 (R–K). This study is the first to report the isolation of PPV in Argentina and the results suggest that PPV can cross the placenta even in vaccinated sows, thus affecting some of the fetuses and being able to cause fetal death in sows without reproductive failure. The results also suggest that vaccination only reduces clinical signs and reproductive disorders and may thus not be a perfect tool to manage PPV infection. This study provides information that needs to be studied in depth to improve strategies to prevent and control PPV infection in swine farms.
format Articulo
Articulo
author Serena, María Soledad
Cappuccio, Javier Alejandro
Metz, Germán Ernesto
Aspitia, Carolina Gabriela
Dibárbora, M.
Gallo Calderón, M.
Echeverría, María Gabriela
author_facet Serena, María Soledad
Cappuccio, Javier Alejandro
Metz, Germán Ernesto
Aspitia, Carolina Gabriela
Dibárbora, M.
Gallo Calderón, M.
Echeverría, María Gabriela
author_sort Serena, María Soledad
title Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina
title_short Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina
title_full Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina
title_fullStr Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina
title_full_unstemmed Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina
title_sort detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in argentina
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/107349
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6881615&blobtype=pdf
work_keys_str_mv AT serenamariasoledad detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
AT cappucciojavieralejandro detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
AT metzgermanernesto detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
AT aspitiacarolinagabriela detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
AT dibarboram detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
AT gallocalderonm detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
AT echeverriamariagabriela detectionandmolecularcharacterizationofporcineparvovirusinfetaltissuesfromsowswithoutreproductivefailureinargentina
bdutipo_str Repositorios
_version_ 1764820442989723648

Ejemplares similares