Population structure in Argentina
We analyzed 391 samples from 12 Argentinian populations from the Center-West, East and North-West regions with the Illumina Human Exome Beadchip v1.0 (HumanExome-12v1- A). We did Principal Components analysis to infer patterns of populational divergence and migrations. We identified proportions and...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/106935 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5929549&blobtype=pdf |
| Aporte de: |
| id |
I19-R120-10915-106935 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Biología Argentinian populations Ancestry |
| spellingShingle |
Biología Argentinian populations Ancestry Muzzio, Marina Motti, Josefina María Brenda Paz Sepúlveda, Paula Beatriz Yee, Muh-Ching Cooke, Thomas Santos, María Rita Ramallo, Virginia Alfaro Gómez, Emma Laura Dipierri, José Edgardo Bailliet, Graciela Bravi, Claudio Marcelo Bustamante, Carlos Ariel Kenny, Eimear E. Population structure in Argentina |
| topic_facet |
Biología Argentinian populations Ancestry |
| description |
We analyzed 391 samples from 12 Argentinian populations from the Center-West, East and North-West regions with the Illumina Human Exome Beadchip v1.0 (HumanExome-12v1- A). We did Principal Components analysis to infer patterns of populational divergence and migrations. We identified proportions and patterns of European, African and Native American ancestry and found a correlation between distance to Buenos Aires and proportion of Native American ancestry, where the highest proportion corresponds to the Northernmost populations, which is also the furthest from the Argentinian capital. Most of the European sources are from a South European origin, matching historical records, and we see two different Native American components, one that spreads all over Argentina and another specifically Andean. The highest percentages of African ancestry were in the Center West of Argentina, where the old trade routes took the slaves from Buenos Aires to Chile and Peru.
Subcontinentaly, sources of this African component are represented by both West Africa and groups influenced by the Bantu expansion, the second slightly higher than the first, unlike North America and the Caribbean, where the main source is West Africa. This is reasonable, considering that a large proportion of the ships arriving at the Southern Hemisphere came from Mozambique, Loango and Angola. |
| format |
Articulo Articulo |
| author |
Muzzio, Marina Motti, Josefina María Brenda Paz Sepúlveda, Paula Beatriz Yee, Muh-Ching Cooke, Thomas Santos, María Rita Ramallo, Virginia Alfaro Gómez, Emma Laura Dipierri, José Edgardo Bailliet, Graciela Bravi, Claudio Marcelo Bustamante, Carlos Ariel Kenny, Eimear E. |
| author_facet |
Muzzio, Marina Motti, Josefina María Brenda Paz Sepúlveda, Paula Beatriz Yee, Muh-Ching Cooke, Thomas Santos, María Rita Ramallo, Virginia Alfaro Gómez, Emma Laura Dipierri, José Edgardo Bailliet, Graciela Bravi, Claudio Marcelo Bustamante, Carlos Ariel Kenny, Eimear E. |
| author_sort |
Muzzio, Marina |
| title |
Population structure in Argentina |
| title_short |
Population structure in Argentina |
| title_full |
Population structure in Argentina |
| title_fullStr |
Population structure in Argentina |
| title_full_unstemmed |
Population structure in Argentina |
| title_sort |
population structure in argentina |
| publishDate |
2018 |
| url |
http://sedici.unlp.edu.ar/handle/10915/106935 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5929549&blobtype=pdf |
| work_keys_str_mv |
AT muzziomarina populationstructureinargentina AT mottijosefinamariabrenda populationstructureinargentina AT pazsepulvedapaulabeatriz populationstructureinargentina AT yeemuhching populationstructureinargentina AT cookethomas populationstructureinargentina AT santosmariarita populationstructureinargentina AT ramallovirginia populationstructureinargentina AT alfarogomezemmalaura populationstructureinargentina AT dipierrijoseedgardo populationstructureinargentina AT baillietgraciela populationstructureinargentina AT braviclaudiomarcelo populationstructureinargentina AT bustamantecarlosariel populationstructureinargentina AT kennyeimeare populationstructureinargentina |
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Repositorios |
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1764820443452145666 |