Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats

The hypocholesterolemic effect of amaranth was studied in male Wistar rats fed a high-fat diet that was supplemented with amaranth flour, AF, or isolated protein, AI. Likewise, an in vitro test was carried out, in which the capacity of the AI, AF, the digested isolate, DAI, and the digested amaranth...

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Detalles Bibliográficos
Autores principales: Sisti, Martín Sebastián, Scilingo, Adriana Alicia, Añón, María Cristina
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Química
amaranth
cholesterol
hypocholesterolemia
fiber
peptides
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/105690
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-105690
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
amaranth
cholesterol
hypocholesterolemia
fiber
peptides
spellingShingle Química
amaranth
cholesterol
hypocholesterolemia
fiber
peptides
Sisti, Martín Sebastián
Scilingo, Adriana Alicia
Añón, María Cristina
Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats
topic_facet Química
amaranth
cholesterol
hypocholesterolemia
fiber
peptides
description The hypocholesterolemic effect of amaranth was studied in male Wistar rats fed a high-fat diet that was supplemented with amaranth flour, AF, or isolated protein, AI. Likewise, an in vitro test was carried out, in which the capacity of the AI, AF, the digested isolate, DAI, and the digested amaranth flour, DAF, to displace the cholesterol of the model micelles was evaluated. The in vivo results showed an increase in the excretion of cholesterol through feces (77% for AF7; 23% and 108% for AI30 and AF30, respect control) and a decrease in the content of hepatic cholesterol (98% for AF7; 96% and 53% for AI30 and AF30 respect control); whereas in vitro it was shown that both AF and DAF have greater power to displace cholesterol than the AI and DAI (IC50 0.1, 0.71, 0.2, and 2.1 for AF, DAF, AI, and DAI, respectively). These evidences show that the proteins and fibers of amaranth have an effect on cholesterol metabolism.
format Articulo
Articulo
author Sisti, Martín Sebastián
Scilingo, Adriana Alicia
Añón, María Cristina
author_facet Sisti, Martín Sebastián
Scilingo, Adriana Alicia
Añón, María Cristina
author_sort Sisti, Martín Sebastián
title Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats
title_short Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats
title_full Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats
title_fullStr Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats
title_full_unstemmed Effect of the Incorporation of Amaranth (<i>Amaranthus Mantegazzianus</i>) into Fat- and Cholesterol-Rich Diets for Wistar Rats
title_sort effect of the incorporation of amaranth (<i>amaranthus mantegazzianus</i>) into fat- and cholesterol-rich diets for wistar rats
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/105690
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