Current strategies to prevent ishcemia reperfusion injury in organ transplantation

Solid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by reperfusion. Several strategies have been proposed to...

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Detalles Bibliográficos
Autores principales:	Stringa, Pablo Luis, Rumbo, Martín
Formato:	Articulo Revision
Lenguaje:	Inglés
Publicado:	2014
Materias:	Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/102619 https://ri.conicet.gov.ar/11336/33219 http://pmr.safisiol.org.ar/archive/id/65
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-102619
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention
spellingShingle	Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention Stringa, Pablo Luis Rumbo, Martín Current strategies to prevent ishcemia reperfusion injury in organ transplantation
topic_facet	Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention
description	Solid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by reperfusion. Several strategies have been proposed to mitigate IRI in organ transplantation.However, most of them are in experimental phases and currently few are implemented in the clinical field. These strategies can be applied in 3 different stages of the transplantation procedure: on the organ donor, known as donor pre-treatment; during preservation, when ischemic organ is waiting to be implanted in the recipient or on the transplant recipient. In the present review, we will discuss the different approaches to control IRI damage in solid organ transplantation and the rationale behind them.
format	Articulo Revision
author	Stringa, Pablo Luis Rumbo, Martín
author_facet	Stringa, Pablo Luis Rumbo, Martín
author_sort	Stringa, Pablo Luis
title	Current strategies to prevent ishcemia reperfusion injury in organ transplantation
title_short	Current strategies to prevent ishcemia reperfusion injury in organ transplantation
title_full	Current strategies to prevent ishcemia reperfusion injury in organ transplantation
title_fullStr	Current strategies to prevent ishcemia reperfusion injury in organ transplantation
title_full_unstemmed	Current strategies to prevent ishcemia reperfusion injury in organ transplantation
title_sort	current strategies to prevent ishcemia reperfusion injury in organ transplantation
publishDate	2014
url	http://sedici.unlp.edu.ar/handle/10915/102619 https://ri.conicet.gov.ar/11336/33219 http://pmr.safisiol.org.ar/archive/id/65
work_keys_str_mv	AT stringapabloluis currentstrategiestopreventishcemiareperfusioninjuryinorgantransplantation AT rumbomartin currentstrategiestopreventishcemiareperfusioninjuryinorgantransplantation
bdutipo_str	Repositorios
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Current strategies to prevent ishcemia reperfusion injury in organ transplantation

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