Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina

Background: Influenza A viruses (IAV) are important pathogens responsible for economic losses in the swine industry and represent a threat to public health. In Argentina, clinical, pathological, and virological findings suggest that IAV infection is widespread among pig farms. In addition, several s...

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Detalles Bibliográficos
Autores principales: Dibárbora, Marina, Cappuccio, Javier A., Olivera, Valeria, Quiroga, María Alejandra, Machuca, Mariana Alejandra, Perfumo, Carlos Juan, Pérez, Daniel Roberto, Pereda, Ariel Julián
Formato: Articulo
Lenguaje:Inglés
Publicado: 2013
Materias:
Ciencias Veterinarias
Argentina
Influenza
Pathology
Serology
Swine
Virology
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/102081
https://ri.conicet.gov.ar/11336/24278
http://onlinelibrary.wiley.com/doi/10.1111/irv.12200/abstract
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-102081
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Argentina
Influenza
Pathology
Serology
Swine
Virology
spellingShingle Ciencias Veterinarias
Argentina
Influenza
Pathology
Serology
Swine
Virology
Dibárbora, Marina
Cappuccio, Javier A.
Olivera, Valeria
Quiroga, María Alejandra
Machuca, Mariana Alejandra
Perfumo, Carlos Juan
Pérez, Daniel Roberto
Pereda, Ariel Julián
Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina
topic_facet Ciencias Veterinarias
Argentina
Influenza
Pathology
Serology
Swine
Virology
description Background: Influenza A viruses (IAV) are important pathogens responsible for economic losses in the swine industry and represent a threat to public health. In Argentina, clinical, pathological, and virological findings suggest that IAV infection is widespread among pig farms. In addition, several subtypes of IAV, such as pH1N1, H3N2, δ1H1N1, and δ2H1N2, have been reported. Objectives: To evaluate the infection patterns of influenza virus in nine pig farms in Argentina. Methods: Clinical, serological, pathological, and virological cross-sectional studies were conducted. Results: Clinical and pathological results were characteristic of endemic influenza infection in eight of the nine farms studied. By rRT-PCR, six of the nine farms were positive to influenza. Five IAV were obtained. Genome analysis determined that four of the isolations were pH1N1 and that the remaining one was a reassortant human origin H3N2 virus containing pandemic internal genes. Serological results showed that all farms were positive to influenza A antibodies. Moreover, the hemagglutination inhibition test showed that infection with viruses containing HA′s from different subtypes (pH1, δ1H1, δ2H1, and H3) is present among the farms studied and that coinfections with two or more subtypes were present in 80.5% of positive pigs. Conclusions: Because vaccines against IAV are not licensed in Argentina, these results reflect the situation of IAV infection in non-vaccinated herds. This study provides more information about the circulation and characteristics of IAV in a poorly surveyed region. This study provides more data that will be used to evaluate the tools necessary to control this disease.
format Articulo
Articulo
author Dibárbora, Marina
Cappuccio, Javier A.
Olivera, Valeria
Quiroga, María Alejandra
Machuca, Mariana Alejandra
Perfumo, Carlos Juan
Pérez, Daniel Roberto
Pereda, Ariel Julián
author_facet Dibárbora, Marina
Cappuccio, Javier A.
Olivera, Valeria
Quiroga, María Alejandra
Machuca, Mariana Alejandra
Perfumo, Carlos Juan
Pérez, Daniel Roberto
Pereda, Ariel Julián
author_sort Dibárbora, Marina
title Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina
title_short Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina
title_full Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina
title_fullStr Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina
title_full_unstemmed Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina
title_sort swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in argentina
publishDate 2013
url http://sedici.unlp.edu.ar/handle/10915/102081
https://ri.conicet.gov.ar/11336/24278
http://onlinelibrary.wiley.com/doi/10.1111/irv.12200/abstract
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