Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls

Puberty is a stage of sexual development determined by the interaction of many loci and environmental factors. Identification of genes contributing to genetic variation in this character can assist with selection for early pubertal bulls, improving genetic progress in livestock breeding. Thyroid hor...

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Detalles Bibliográficos
Autores principales: Fernández, María Elena, Goszczynski, Daniel Estanislao, Prando, Alberto José, Peral García, Pilar, Baldo, Andrés, Giovambattista, Guillermo, Lirón, Juan Pedro
Formato: Articulo
Lenguaje:Inglés
Publicado: 2014
Materias:
Ciencias Veterinarias
Bovine
Puberty
Polymorphism
Thyroglobulin
Association study
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/100592
https://ri.conicet.gov.ar/11336/11791
http://janimscitechnol.biomedcentral.com/articles/10.1186/2055-0391-56-17
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-100592
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Bovine
Puberty
Polymorphism
Thyroglobulin
Association study
spellingShingle Ciencias Veterinarias
Bovine
Puberty
Polymorphism
Thyroglobulin
Association study
Fernández, María Elena
Goszczynski, Daniel Estanislao
Prando, Alberto José
Peral García, Pilar
Baldo, Andrés
Giovambattista, Guillermo
Lirón, Juan Pedro
Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
topic_facet Ciencias Veterinarias
Bovine
Puberty
Polymorphism
Thyroglobulin
Association study
description Puberty is a stage of sexual development determined by the interaction of many loci and environmental factors. Identification of genes contributing to genetic variation in this character can assist with selection for early pubertal bulls, improving genetic progress in livestock breeding. Thyroid hormones play an important role in sexual development and spermatogenic function. The objective of this study was to evaluate the association between single nucleotide polymorphisms (SNPs) located in thyroglobulin(TG) gene with age of puberty in Angus bulls. Four SNPs were genotyped in 273 animals using SEQUENOM technology and the association between markers and puberty age was analyzed. Results showed a significant association (P < 0.05) between these markers and puberty age estimated at a sperm concentration of 50 million and a progressive motility of 10%. This is the first report of an association of TG polymorphisms with age of puberty in bulls, and results suggest the importance of thyroidal regulation in bovine sexual development and arrival to puberty.
format Articulo
Articulo
author Fernández, María Elena
Goszczynski, Daniel Estanislao
Prando, Alberto José
Peral García, Pilar
Baldo, Andrés
Giovambattista, Guillermo
Lirón, Juan Pedro
author_facet Fernández, María Elena
Goszczynski, Daniel Estanislao
Prando, Alberto José
Peral García, Pilar
Baldo, Andrés
Giovambattista, Guillermo
Lirón, Juan Pedro
author_sort Fernández, María Elena
title Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
title_short Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
title_full Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
title_fullStr Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
title_full_unstemmed Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
title_sort assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
publishDate 2014
url http://sedici.unlp.edu.ar/handle/10915/100592
https://ri.conicet.gov.ar/11336/11791
http://janimscitechnol.biomedcentral.com/articles/10.1186/2055-0391-56-17
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