Prenatal sonographic detection of birth defects in 18 hospitals from South America

Objective. The purpose of this study was to assess the accuracy of prenatal sonographic diagnosis of birth defects and the gestational age at detection according to the health insurance schemes of mothers in 450 malformed neonates from 18 South American hospitals on the basis of prenatal sonographic...

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Autores principales: Campaña, Hebe, Ermini, Mónica, Aiello, Horacio A., Krupitzki, Hugo Bernardo, Castilla, Eduardo Enrique, López Camelo, Jorge Santiago
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/100533
https://ri.conicet.gov.ar/11336/53833
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id I19-R120-10915-100533
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Birth defects
Health insurance scheme
Latin american collaborative study of congenital malformations
Prenatal sonography
South America
spellingShingle Ciencias Médicas
Birth defects
Health insurance scheme
Latin american collaborative study of congenital malformations
Prenatal sonography
South America
Campaña, Hebe
Ermini, Mónica
Aiello, Horacio A.
Krupitzki, Hugo Bernardo
Castilla, Eduardo Enrique
López Camelo, Jorge Santiago
Prenatal sonographic detection of birth defects in 18 hospitals from South America
topic_facet Ciencias Médicas
Birth defects
Health insurance scheme
Latin american collaborative study of congenital malformations
Prenatal sonography
South America
description Objective. The purpose of this study was to assess the accuracy of prenatal sonographic diagnosis of birth defects and the gestational age at detection according to the health insurance schemes of mothers in 450 malformed neonates from 18 South American hospitals on the basis of prenatal sonographic records. Methods. Between July 2000 and December 2003, 18 hospitals included in the Latin American Collaborative Study of Congenital Malformations (13 from Argentina [8 public and 5 nonpublic], 3 from Brazil [2 public and 1 nonpublic], 1 from Chile [nonpublic], and 1 from Venezuela [public]) voluntarily participated in this prospective observational study, recording fetuses with sonographically detected malformations. Prenatal sonographic descriptions of anomalies were compared with those recorded at birth. Results. Of 812 anomalies detected at birth, 457 had been prenatally detected (detection rate, 56.3%; 95% confidence interval, 52.8%-59.8%). Before 24 gestational weeks, anencephaly had the highest detection rate. Cleft lip and clubfoot were more easily detected when associated with other anomalies. The detection rates for central nervous system and renourinary malformations were greater than 80%. Detection rates between both health insurance schemes (public and nonpublic) did not show significant differences, but anencephaly, spina bifida, renourinary defects, and cleft lip with or without cleft palate were detected earlier in patients from nonpublic rather than in public hospitals. Conclusions. For specific anomalies, South America shows similar levels of prenatal sonographic detection as developed countries. Detection rates during pregnancy were similar for public and nonpublic hospitals, whereas cases were diagnosed earlier in patients from nonpublic hospitals.
format Articulo
Articulo
author Campaña, Hebe
Ermini, Mónica
Aiello, Horacio A.
Krupitzki, Hugo Bernardo
Castilla, Eduardo Enrique
López Camelo, Jorge Santiago
author_facet Campaña, Hebe
Ermini, Mónica
Aiello, Horacio A.
Krupitzki, Hugo Bernardo
Castilla, Eduardo Enrique
López Camelo, Jorge Santiago
author_sort Campaña, Hebe
title Prenatal sonographic detection of birth defects in 18 hospitals from South America
title_short Prenatal sonographic detection of birth defects in 18 hospitals from South America
title_full Prenatal sonographic detection of birth defects in 18 hospitals from South America
title_fullStr Prenatal sonographic detection of birth defects in 18 hospitals from South America
title_full_unstemmed Prenatal sonographic detection of birth defects in 18 hospitals from South America
title_sort prenatal sonographic detection of birth defects in 18 hospitals from south america
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/100533
https://ri.conicet.gov.ar/11336/53833
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