Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.

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Encephalitis associated with anti—N—methyl—D—aspartate (NMDA) receptor antibodies is an autoimmune neurological condition recently recognized in 2007. It mainly affects young adults—especially women—and children. A large percentage is associated with tumour processes. Patients develop neuropsychiatr...

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Autores principales: Palm, Julieta, Labaronnie, Eugenia, Bassi, Gianna, Lingua, Emiliano, Pendino, Juan C., Parodi, Roberto, Lupo, Sergio
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional de Rosario 2021
Materias:
Anticuerpos
Antirreceptor n—metil—d—aspartato
Encefalitis eutounmune
Receptores de n—metil—d—aspartato
Síntomas neuropsiquiátricos
Antibodies
Anti—n—methyl—d—aspartate receptor
Autoinmmune encephalitis
N—methyl—d—aspartate receptors
Neuropsychiatric symptoms
Acceso en línea:https://fcmcientifica.unr.edu.ar/index.php/revista/article/view/33
Aporte de:
FCM Científica de Universidad Nacional de Rosario
id I15-R235-article-33
record_format ojs
spelling I15-R235-article-332022-07-07T12:22:47Z Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report. Encefalitis por anticuerpos antirreceptor de n-metil-d-aspartato. Reporte de caso. Palm, Julieta Labaronnie, Eugenia Bassi, Gianna Lingua, Emiliano Pendino, Juan C. Parodi, Roberto Lupo, Sergio Anticuerpos Antirreceptor n—metil—d—aspartato Encefalitis eutounmune Receptores de n—metil—d—aspartato Síntomas neuropsiquiátricos Antibodies Anti—n—methyl—d—aspartate receptor Autoinmmune encephalitis N—methyl—d—aspartate receptors Neuropsychiatric symptoms Encephalitis associated with anti—N—methyl—D—aspartate (NMDA) receptor antibodies is an autoimmune neurological condition recently recognized in 2007. It mainly affects young adults—especially women—and children. A large percentage is associated with tumour processes. Patients develop neuropsychiatric symptoms in a rapid and sequential way and they have convulsive crises that rapidly result in decreasing levels of consciousness, mutism, catatonia and abnormal movements. It is a potentially reversible condition and the seriousness of its effects will depend on how soon the patient receives treatment. This paper describes the case of a young patient who initially displayed self—injurious behaviour and had hallucinations. Later, he had memory and language impairment, behavioral disorders, seizures and anti—NMDA receptor antibodies in the cerebrospinal fluid. He had a favourable response to immunoglobulins and corticosteroids with control and stabilization of the disease. La encefalitis por anticuerpos contra el receptor N—metil—D— aspartato (NMDA) es una patología neurológica autoinmune reconocida recientemente en el año 2007 que afecta principalmente a adultos jóvenes, predominantemente mujeres y niños. Un gran porcentaje está asociado a procesos tumorales. Clínicamente los pacientes desarrollan de manera rápida y secuencial síntomas neuropsiquiátricos, crisis convulsivas que progresan hacia un rápido deterioro del nivel de consciencia, mutismo, catatonía y movimientos anormales. Es una patología potencialmente reversible y el grado de secuelas va a depender de la rapidez en el inicio del tratamiento. Se presenta el caso de un paciente joven que debutó con conductas autoagresivas y alucinaciones. Cursó posteriormente con trastornos de memoria y lenguaje, alteraciones conductuales y convulsiones y presentó anticuerpos contra receptores NMDA en el líquido cefalorraquídeo (LCR). Realizó tratamiento con inmunoglobulinas y corticoides con evolución favorable logrando control y no progreso de la enfermedad. Universidad Nacional de Rosario 2021-06-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://fcmcientifica.unr.edu.ar/index.php/revista/article/view/33 10.35305/fcm.v1i.33 Revista de la Facultad de Ciencias Médicas. Universidad Nacional de Rosario.; Vol. 1 (2020); 161-165 2796-7719 spa https://fcmcientifica.unr.edu.ar/index.php/revista/article/view/33/49 https://creativecommons.org/licenses/by-nc/4.0/
institution Universidad Nacional de Rosario
institution_str I-15
repository_str R-235
container_title_str FCM Científica
language Español
format Artículo revista
topic Anticuerpos
Antirreceptor n—metil—d—aspartato
Encefalitis eutounmune
Receptores de n—metil—d—aspartato
Síntomas neuropsiquiátricos
Antibodies
Anti—n—methyl—d—aspartate receptor
Autoinmmune encephalitis
N—methyl—d—aspartate receptors
Neuropsychiatric symptoms
spellingShingle Anticuerpos
Antirreceptor n—metil—d—aspartato
Encefalitis eutounmune
Receptores de n—metil—d—aspartato
Síntomas neuropsiquiátricos
Antibodies
Anti—n—methyl—d—aspartate receptor
Autoinmmune encephalitis
N—methyl—d—aspartate receptors
Neuropsychiatric symptoms
Palm, Julieta
Labaronnie, Eugenia
Bassi, Gianna
Lingua, Emiliano
Pendino, Juan C.
Parodi, Roberto
Lupo, Sergio
Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.
topic_facet Anticuerpos
Antirreceptor n—metil—d—aspartato
Encefalitis eutounmune
Receptores de n—metil—d—aspartato
Síntomas neuropsiquiátricos
Antibodies
Anti—n—methyl—d—aspartate receptor
Autoinmmune encephalitis
N—methyl—d—aspartate receptors
Neuropsychiatric symptoms
author Palm, Julieta
Labaronnie, Eugenia
Bassi, Gianna
Lingua, Emiliano
Pendino, Juan C.
Parodi, Roberto
Lupo, Sergio
author_facet Palm, Julieta
Labaronnie, Eugenia
Bassi, Gianna
Lingua, Emiliano
Pendino, Juan C.
Parodi, Roberto
Lupo, Sergio
author_sort Palm, Julieta
title Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.
title_short Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.
title_full Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.
title_fullStr Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.
title_full_unstemmed Encephalitis associated with Anti-n-methyl-d-aspartate receptor antibodies. Case report.
title_sort encephalitis associated with anti-n-methyl-d-aspartate receptor antibodies. case report.
description Encephalitis associated with anti—N—methyl—D—aspartate (NMDA) receptor antibodies is an autoimmune neurological condition recently recognized in 2007. It mainly affects young adults—especially women—and children. A large percentage is associated with tumour processes. Patients develop neuropsychiatric symptoms in a rapid and sequential way and they have convulsive crises that rapidly result in decreasing levels of consciousness, mutism, catatonia and abnormal movements. It is a potentially reversible condition and the seriousness of its effects will depend on how soon the patient receives treatment. This paper describes the case of a young patient who initially displayed self—injurious behaviour and had hallucinations. Later, he had memory and language impairment, behavioral disorders, seizures and anti—NMDA receptor antibodies in the cerebrospinal fluid. He had a favourable response to immunoglobulins and corticosteroids with control and stabilization of the disease.
publisher Universidad Nacional de Rosario
publishDate 2021
url https://fcmcientifica.unr.edu.ar/index.php/revista/article/view/33
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first_indexed 2023-06-26T22:50:58Z
last_indexed 2023-06-26T22:50:58Z
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