Use of Annexin V based Sperm Selection in Assisted Reproduction

Innovative methods to select sperm subpopulations with the best fertilizing ability are needed in assisted reproductive techniques (ART) in order to improve fertilization and pregnancy rates, while also considering possible epigenetic effects on the offspring. Molecular based selection methods are...

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Autores principales:	Teijeiro, Juan Manuel, Munuce, María José, Caille, Adriana María, Zumoffen, Carlos, Marini, Patricia Estela
Formato:	article artículo publishedVersion
Lenguaje:	Inglés
Publicado:	OMICS International 2017
Materias:	Anexina A5 selección de espermatozoides técnicas de reproducción asistida Annexin A5 Sperm selection Assisted reproductive techniques
Acceso en línea:	http://hdl.handle.net/2133/9267 http://hdl.handle.net/2133/9267
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

id	I15-R121-2133-9267
record_format	dspace
institution	Universidad Nacional de Rosario
institution_str	I-15
repository_str	R-121
collection	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR)
language	Inglés
orig_language_str_mv	eng
topic	Anexina A5 selección de espermatozoides técnicas de reproducción asistida Annexin A5 Sperm selection Assisted reproductive techniques
spellingShingle	Anexina A5 selección de espermatozoides técnicas de reproducción asistida Annexin A5 Sperm selection Assisted reproductive techniques Teijeiro, Juan Manuel Munuce, María José Caille, Adriana María Zumoffen, Carlos Marini, Patricia Estela Use of Annexin V based Sperm Selection in Assisted Reproduction
topic_facet	Anexina A5 selección de espermatozoides técnicas de reproducción asistida Annexin A5 Sperm selection Assisted reproductive techniques
description	Innovative methods to select sperm subpopulations with the best fertilizing ability are needed in assisted reproductive techniques (ART) in order to improve fertilization and pregnancy rates, while also considering possible epigenetic effects on the offspring. Molecular based selection methods are searched for, under the premise that they could be an improvement over classical selection by morphology and movement. One of these methods sustains the elimination of sperm that can bind to annexin A5 (ANX V), coupled to paramagnetic beads, through the phosphatidyl-serine exposed on their membranes upon apoptosis. Although reports accumulate about the use of this method, controversy persists as to the benefits of ANX V based sperm selection in ART. In this review we consider the arguments in favour and against this method and conclude that to the moment the evidence does not support MACS regular use in ART.
format	article artículo publishedVersion
author	Teijeiro, Juan Manuel Munuce, María José Caille, Adriana María Zumoffen, Carlos Marini, Patricia Estela
author_facet	Teijeiro, Juan Manuel Munuce, María José Caille, Adriana María Zumoffen, Carlos Marini, Patricia Estela
author_sort	Teijeiro, Juan Manuel
title	Use of Annexin V based Sperm Selection in Assisted Reproduction
title_short	Use of Annexin V based Sperm Selection in Assisted Reproduction
title_full	Use of Annexin V based Sperm Selection in Assisted Reproduction
title_fullStr	Use of Annexin V based Sperm Selection in Assisted Reproduction
title_full_unstemmed	Use of Annexin V based Sperm Selection in Assisted Reproduction
title_sort	use of annexin v based sperm selection in assisted reproduction
publisher	OMICS International
publishDate	2017
url	http://hdl.handle.net/2133/9267 http://hdl.handle.net/2133/9267
work_keys_str_mv	AT teijeirojuanmanuel useofannexinvbasedspermselectioninassistedreproduction AT munucemariajose useofannexinvbasedspermselectioninassistedreproduction AT cailleadrianamaria useofannexinvbasedspermselectioninassistedreproduction AT zumoffencarlos useofannexinvbasedspermselectioninassistedreproduction AT marinipatriciaestela useofannexinvbasedspermselectioninassistedreproduction
bdutipo_str	Repositorios
_version_	1764820413817290754

Use of Annexin V based Sperm Selection in Assisted Reproduction

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