Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)

The endophytic fungal community associated with leaves of Ficus carica L. (Moraceae) from Argentina was investigated. Fifteen fungal isolates were isolated and identified by molecular methods into the genera Alternaria, Cladosporium, Curvularia, Diaporthe, Epicoccum, Myrothecium, Neofusicoccum, Nigr...

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Autores principales: Barolo, Melisa Isabel, Castelli, María Victoria, López, Silvia Noelí
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Taylor and Francis Ltd. 2023
Materias:
Endophytic fungi
Ficus carica
Chemical profiling
Antimicrobial activity
Biotransformation
Acceso en línea:http://hdl.handle.net/2133/25424
http://hdl.handle.net/2133/25424
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario
id I15-R121-2133-25424
record_format dspace
institution Universidad Nacional de Rosario
institution_str I-15
repository_str R-121
collection Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR)
language Inglés
topic Endophytic fungi
Ficus carica
Chemical profiling
Antimicrobial activity
Biotransformation
spellingShingle Endophytic fungi
Ficus carica
Chemical profiling
Antimicrobial activity
Biotransformation
Barolo, Melisa Isabel
Castelli, María Victoria
López, Silvia Noelí
Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)
topic_facet Endophytic fungi
Ficus carica
Chemical profiling
Antimicrobial activity
Biotransformation
description The endophytic fungal community associated with leaves of Ficus carica L. (Moraceae) from Argentina was investigated. Fifteen fungal isolates were isolated and identified by molecular methods into the genera Alternaria, Cladosporium, Curvularia, Diaporthe, Epicoccum, Myrothecium, Neofusicoccum, Nigrospora, Preussia and Ustilago. Cladosporium cladosporioides and Curvularia lunata were the most frequently isolated species. The fungal metabolic profiles were obtained by automated TLC and NMR and analysed by PC Analysis. Antifungal and antibacterial activity was assessed by bioautographic assays. In addition, the biotransforming ability of the fungal isolates was tested on F. carica extracts. Five isolates (33.3%) exhibited inhibitory activity against at least one of the microorganisms tested. Most of the fungal endophytes were able to metabolise the flavonoid rutin 1, and the coumarin psoralen 3 present in F. carica extracts. Further investigations of the psoralen biotransforming ability performed by the selected endophyte Alternaria alternata F8 showed the accumulation of the 6,7-furan-hydrocoumaric acid derivative 4 as the main biotransformation product. Our results corroborate that F. carica can live symbioti-cally with rich and diverse endophytic communities adding insights about their ecological interactions.
format article
artículo
publishedVersion
author Barolo, Melisa Isabel
Castelli, María Victoria
López, Silvia Noelí
author_facet Barolo, Melisa Isabel
Castelli, María Victoria
López, Silvia Noelí
author_sort Barolo, Melisa Isabel
title Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)
title_short Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)
title_full Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)
title_fullStr Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)
title_full_unstemmed Antimicrobial properties and biotransforming ability of fungal endophytes from Ficus carica L. (Moraceae)
title_sort antimicrobial properties and biotransforming ability of fungal endophytes from ficus carica l. (moraceae)
publisher Taylor and Francis Ltd.
publishDate 2023
url http://hdl.handle.net/2133/25424
http://hdl.handle.net/2133/25424
work_keys_str_mv AT barolomelisaisabel antimicrobialpropertiesandbiotransformingabilityoffungalendophytesfromficuscaricalmoraceae
AT castellimariavictoria antimicrobialpropertiesandbiotransformingabilityoffungalendophytesfromficuscaricalmoraceae
AT lopezsilvianoeli antimicrobialpropertiesandbiotransformingabilityoffungalendophytesfromficuscaricalmoraceae
bdutipo_str Repositorios
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