Aquaporins as targets of dietary bioactive phytocompounds

Plant-derived bioactive compounds have protective role for plants but may also modulate several physiological processes of plant consumers. In the last years, a wide spectrum of phytochemicals have been found to be beneficial to health interacting with molecular signaling pathways underlying crit...

Descripción completa

Detalles Bibliográficos
Autores principales: Tesse, Angela, Grossini, Elena, Tamma, Grazia, Brenner, Catherine, Portincasa, Piero, Marinelli, Raúl A., Calamita, Giuseppe
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Frontiers Media 2021
Materias:
Acceso en línea:http://hdl.handle.net/2133/19957
http://hdl.handle.net/2133/19957
Aporte de:
id I15-R121-2133-19957
record_format dspace
institution Universidad Nacional de Rosario
institution_str I-15
repository_str R-121
collection Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR)
language Inglés
orig_language_str_mv eng
topic Aquaporin Membrane Channels
Functional Food
Nutraceutics
Epigenomics
Gastrointestinal Microbiome
Antioxidants
Anti-Inflammatory Agents
spellingShingle Aquaporin Membrane Channels
Functional Food
Nutraceutics
Epigenomics
Gastrointestinal Microbiome
Antioxidants
Anti-Inflammatory Agents
Tesse, Angela
Grossini, Elena
Tamma, Grazia
Brenner, Catherine
Portincasa, Piero
Marinelli, Raúl A.
Calamita, Giuseppe
Aquaporins as targets of dietary bioactive phytocompounds
topic_facet Aquaporin Membrane Channels
Functional Food
Nutraceutics
Epigenomics
Gastrointestinal Microbiome
Antioxidants
Anti-Inflammatory Agents
description Plant-derived bioactive compounds have protective role for plants but may also modulate several physiological processes of plant consumers. In the last years, a wide spectrum of phytochemicals have been found to be beneficial to health interacting with molecular signaling pathways underlying critical functions such as cell growth and differentiation, apoptosis, autophagy, inflammation, redox balance, cell volume regulation, metabolic homeostasis, and energy balance. Hence, a large number of biologically active phytocompounds of foods have been isolated, characterized, and eventually modified representing a natural source of novel molecules to prevent, delay or cure several human diseases. Aquaporins (AQPs), a family of membrane channel proteins involved in many body functions, are emerging among the targets of bioactive phytochemicals in imparting their beneficial actions. Here, we provide a comprehensive review of this fast growing topic focusing especially on what it is known on the modulatory effects played by several edible plant and herbal compounds on AQPs, both in health and disease. Phytochemical modulation of AQP expression may provide new medical treatment options to improve the prognosis of several diseases.
format article
artículo
publishedVersion
author Tesse, Angela
Grossini, Elena
Tamma, Grazia
Brenner, Catherine
Portincasa, Piero
Marinelli, Raúl A.
Calamita, Giuseppe
author_facet Tesse, Angela
Grossini, Elena
Tamma, Grazia
Brenner, Catherine
Portincasa, Piero
Marinelli, Raúl A.
Calamita, Giuseppe
author_sort Tesse, Angela
title Aquaporins as targets of dietary bioactive phytocompounds
title_short Aquaporins as targets of dietary bioactive phytocompounds
title_full Aquaporins as targets of dietary bioactive phytocompounds
title_fullStr Aquaporins as targets of dietary bioactive phytocompounds
title_full_unstemmed Aquaporins as targets of dietary bioactive phytocompounds
title_sort aquaporins as targets of dietary bioactive phytocompounds
publisher Frontiers Media
publishDate 2021
url http://hdl.handle.net/2133/19957
http://hdl.handle.net/2133/19957
work_keys_str_mv AT tesseangela aquaporinsastargetsofdietarybioactivephytocompounds
AT grossinielena aquaporinsastargetsofdietarybioactivephytocompounds
AT tammagrazia aquaporinsastargetsofdietarybioactivephytocompounds
AT brennercatherine aquaporinsastargetsofdietarybioactivephytocompounds
AT portincasapiero aquaporinsastargetsofdietarybioactivephytocompounds
AT marinelliraula aquaporinsastargetsofdietarybioactivephytocompounds
AT calamitagiuseppe aquaporinsastargetsofdietarybioactivephytocompounds
bdutipo_str Repositorios
_version_ 1764820411205287936