Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome
The gold-catalyzed intermolecular hydroalkylation of olefins with β-ketoesters represents a conceptually attractive and useful synthetic tool; however, it has been scarcely applied, remaining a challenge for chemists. The aim of the current study was to investigate the addition of these 1,3-diket...
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| Autores principales: | , , |
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| Formato: | article artículo publishedVersion |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/2133/19506 http://hdl.handle.net/2133/19506 |
| Aporte de: |
| id |
I15-R121-2133-19506 |
|---|---|
| record_format |
dspace |
| institution |
Universidad Nacional de Rosario |
| institution_str |
I-15 |
| repository_str |
R-121 |
| collection |
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) |
| language |
Inglés |
| orig_language_str_mv |
eng |
| topic |
Catalysis Gold Hydroalkylation beta-Ketoesters Alkenes |
| spellingShingle |
Catalysis Gold Hydroalkylation beta-Ketoesters Alkenes La Venia, Agustina Mischne, Mirta P. Mata, Ernesto Gabino Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| topic_facet |
Catalysis Gold Hydroalkylation beta-Ketoesters Alkenes |
| description |
The gold-catalyzed intermolecular hydroalkylation of olefins with β-ketoesters represents
a conceptually attractive and useful synthetic tool; however, it has been scarcely applied, remaining
a challenge for chemists. The aim of the current study was to investigate the addition of these
1,3-diketo-compounds to alkenes under gold catalysis conditions, in order to establish the electronic
and steric effects of the alkenyl substrates in the reaction outcome. The screening of different catalyst
systems and diverse olefins enabled defining the alkenyl requirements and the best reaction conditions
to efficiently achieve the coupled products. |
| format |
article artículo publishedVersion |
| author |
La Venia, Agustina Mischne, Mirta P. Mata, Ernesto Gabino |
| author_facet |
La Venia, Agustina Mischne, Mirta P. Mata, Ernesto Gabino |
| author_sort |
La Venia, Agustina |
| title |
Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| title_short |
Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| title_full |
Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| title_fullStr |
Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| title_full_unstemmed |
Gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| title_sort |
gold-catalyzed addition of β-ketoesters to alkenes: influence of electronic and steric effects in the reaction outcome |
| publisher |
MDPI |
| publishDate |
2020 |
| url |
http://hdl.handle.net/2133/19506 http://hdl.handle.net/2133/19506 |
| work_keys_str_mv |
AT laveniaagustina goldcatalyzedadditionofbketoesterstoalkenesinfluenceofelectronicandstericeffectsinthereactionoutcome AT mischnemirtap goldcatalyzedadditionofbketoesterstoalkenesinfluenceofelectronicandstericeffectsinthereactionoutcome AT mataernestogabino goldcatalyzedadditionofbketoesterstoalkenesinfluenceofelectronicandstericeffectsinthereactionoutcome |
| bdutipo_str |
Repositorios |
| _version_ |
1764820410905395203 |