Molecular diversity by olefin cross-metathesis on solid support. Generation of libraries of biologically promising β-lactam derivatives

The application of the reagent-based diversification strategy for generation of libraries of biologically promising β-lactam derivatives is described. Key features are the versatility of the linker used and the cross-metathesis functionalization at the cleavage step. From an immobilized primary l...

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Autores principales: Méndez, Luciana, Poeylaut-Palena, Andrés A., Mata, Ernesto Gabino
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: MDPI 2020
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Acceso en línea:http://hdl.handle.net/2133/19505
http://hdl.handle.net/2133/19505
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