Synthesis of new chiral 1,3-aminoalcohols derived from levoglucosenone and their application in asymmetric alkylations

We have developed a simple procedure for the preparation of chiral 1,3-aminoalcohols using the biomass derivative levoglucosenone, as the chiral starting material. 1,3-aminoalcohols, bearing primary and tertiary amino groups, were tested as chiral catalysts in the asymmetric addition of diethyl zinc...

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Autores principales: Zanardi, María Marta, Suárez, Alejandra Graciela
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Elsevier 2018
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Acceso en línea:http://hdl.handle.net/2133/13535
http://hdl.handle.net/2133/13535
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Sumario:We have developed a simple procedure for the preparation of chiral 1,3-aminoalcohols using the biomass derivative levoglucosenone, as the chiral starting material. 1,3-aminoalcohols, bearing primary and tertiary amino groups, were tested as chiral catalysts in the asymmetric addition of diethyl zinc to benzaldehyde.