Effects of chronic nicotine on autoshaping acquisition and extinction

Learning and motivational processes have been central for a modern understanding of tobacco addiction. In particular, there is growing evidence highlighting the importance of incentive motivational processes for the maintenance of tobacco addiction. The present experiment evaluated the effects of ch...

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Autores principales: Ortega, Leonardo, Papini, Mauricio
Formato: Artículo revista
Lenguaje:Inglés
Publicado: Instituto de Investigaciones Psicológicas 2024
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Acceso en línea:https://revistas.unc.edu.ar/index.php/racc/article/view/41760
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spelling I10-R363-article-417602024-12-26T13:31:48Z Effects of chronic nicotine on autoshaping acquisition and extinction Effects of chronic nicotine on autoshaping acquisition and extinction Ortega, Leonardo Papini, Mauricio Ortega, Leonardo Papini, Mauricio Ortega, Leonardo Papini, Mauricio Nicotine addiction autoshaping acquisition extinction incentive motivation nicotine addiction acquisition extinction incentive motivation Learning and motivational processes have been central for a modern understanding of tobacco addiction. In particular, there is growing evidence highlighting the importance of incentive motivational processes for the maintenance of tobacco addiction. The present experiment evaluated the effects of chronic nicotine on the incentive value of a natural reward paired with an environmental cue during acquisition and extinction in a Pavlovian autoshaping procedure with rats. We found that chronic administration of a nicotine dose with translational value for human research had an enhancing effect on responding to an environmental cue during late autoshaping acquisition, but there was no evidence that it affected extinction. Our results are consistent with the role of nicotine enhancing the incentive value of stimuli during acquisition on a Pavlovian autoshaping task and suggest future research on the conditions necessary for the expression of nicotine enhancement in Pavlovian autoshaping tasks. Learning and motivational processes have been central to a modern understanding of tobacco addiction. In particular, there is growing evidence highlighting the importance of incentive motivational processes for the maintenance of tobacco addiction. The present experiment evaluated the effects of chronic nicotine on the incentive value of a natural reward paired with an environmental cue during acquisition and extinction in a Pavlovian autoshaping procedure with rats. We found that chronic administration of a nicotine dose with translational value for human research had an enhancing effect on responding to an environmental cue during late autoshaping acquisition, but there was no evidence that it affected extinction. Our results are consistent with the role of nicotine enhancing the incentive value of stimuli during acquisition on a Pavlovian autoshaping task and suggest future research on the conditions necessary for the expression of nicotine enhancement in Pavlovian autoshaping tasks. Instituto de Investigaciones Psicológicas 2024-12-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/racc/article/view/41760 10.32348/1852.4206.v16.n4.41760 Argentinean Journal of Behavioral Sciences; Vol. 16 No. 4 (2024): Revista Argentina de Ciencias del Comportamiento; 86-95 Revista Argentina de Ciencias del Comportamiento; Vol. 16 Núm. 4 (2024): Revista Argentina de Ciencias del Comportamiento; 86-95 1852-4206 10.32348/1852.4206.v16.n4 eng https://revistas.unc.edu.ar/index.php/racc/article/view/41760/48125 Derechos de autor 2024 Leonardo Ortega, Mauricio Papini http://creativecommons.org/licenses/by/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-363
container_title_str Revista Argentina de Ciencias del Comportamiento
language Inglés
format Artículo revista
topic Nicotine
addiction
autoshaping
acquisition
extinction
incentive motivation
nicotine addiction
acquisition
extinction
incentive motivation
spellingShingle Nicotine
addiction
autoshaping
acquisition
extinction
incentive motivation
nicotine addiction
acquisition
extinction
incentive motivation
Ortega, Leonardo
Papini, Mauricio
Ortega, Leonardo
Papini, Mauricio
Ortega, Leonardo
Papini, Mauricio
Effects of chronic nicotine on autoshaping acquisition and extinction
topic_facet Nicotine
addiction
autoshaping
acquisition
extinction
incentive motivation
nicotine addiction
acquisition
extinction
incentive motivation
author Ortega, Leonardo
Papini, Mauricio
Ortega, Leonardo
Papini, Mauricio
Ortega, Leonardo
Papini, Mauricio
author_facet Ortega, Leonardo
Papini, Mauricio
Ortega, Leonardo
Papini, Mauricio
Ortega, Leonardo
Papini, Mauricio
author_sort Ortega, Leonardo
title Effects of chronic nicotine on autoshaping acquisition and extinction
title_short Effects of chronic nicotine on autoshaping acquisition and extinction
title_full Effects of chronic nicotine on autoshaping acquisition and extinction
title_fullStr Effects of chronic nicotine on autoshaping acquisition and extinction
title_full_unstemmed Effects of chronic nicotine on autoshaping acquisition and extinction
title_sort effects of chronic nicotine on autoshaping acquisition and extinction
description Learning and motivational processes have been central for a modern understanding of tobacco addiction. In particular, there is growing evidence highlighting the importance of incentive motivational processes for the maintenance of tobacco addiction. The present experiment evaluated the effects of chronic nicotine on the incentive value of a natural reward paired with an environmental cue during acquisition and extinction in a Pavlovian autoshaping procedure with rats. We found that chronic administration of a nicotine dose with translational value for human research had an enhancing effect on responding to an environmental cue during late autoshaping acquisition, but there was no evidence that it affected extinction. Our results are consistent with the role of nicotine enhancing the incentive value of stimuli during acquisition on a Pavlovian autoshaping task and suggest future research on the conditions necessary for the expression of nicotine enhancement in Pavlovian autoshaping tasks.
publisher Instituto de Investigaciones Psicológicas
publishDate 2024
url https://revistas.unc.edu.ar/index.php/racc/article/view/41760
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first_indexed 2025-02-05T22:14:59Z
last_indexed 2025-02-05T22:14:59Z
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