Overuse of Acid-Suppressive Therapy in Pediatric Patients
Objectives: To evaluate prescription patterns of intravenous ranitidine and omeprazole in pediatric patients hospitalized in a children’s hospital, the adequacy of said prescriptions and the costs originated by incorrect prescriptions.Patients and Methods: A study of medication usage was designed to...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC
2014
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/RSD/article/view/6911 |
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I10-R360-article-69112025-04-03T12:07:46Z Overuse of Acid-Suppressive Therapy in Pediatric Patients Sobreutilización de inhibidores de la acidez gástrica en pacientes pediátricos Milone, María Caterina Olocco, María Ester Guitart, Xavier Vidal Pediatría Farmacoepidemiología Utilización de Medicamentos Profilaxis de Ulcera por Estrés Errores Médicos Antagonistas de Histamina H2 Inhibidores de la Bomba de Protones Pediatrics Pharmacoepidemiology Drug Utilization Stress Ulcer Prophylaxis Medical Errors Histamine H2 Antagonists Proton Pump Inhibitors Objectives: To evaluate prescription patterns of intravenous ranitidine and omeprazole in pediatric patients hospitalized in a children’s hospital, the adequacy of said prescriptions and the costs originated by incorrect prescriptions.Patients and Methods: A study of medication usage was designed to observe all patients hospitalized at Hospital de Niños (Córdoba- Argentina) during one month.Results: During the month of study 680 patients were hospitalized, 415 (61%) of them received acid-suppressive drugs (ASD). From these, 330 patients (79.5%) did not show risk factors to develop stress ulcer and indications were considered incorrect in 293 patients (70.6%). Only 81 patients (19.5%) showed correct indications and doses of ASD. A relationship was found between prescription and access to the operating room along with the concomitant use of corticoid in low doses. The unnecessary consumption of ASD generated a direct monthly expenditure of USD 470.42.Conclusions: This study shows an alarming overuse of ASD in the pediatric population at Hospital de Niños. There exists a gap between scientific tests and everyday clinical practice in ASD use. Educational strategies should be implemented in pharmacotherapy using response protocols and pharmacology audits with posterior assessment to improve the use of medications and provide patients with an effective, safe, high-quality and academic medicine. Objetivos: Evaluar los patrones de prescripción de ranitidina y omeprazol en pacientes pediátricos ingresados en un hospital de niños; la adecuación de dichas prescripciones y los costos generados por prescripciones incorrectas.Pacientes y Métodos: estudio de utilización de medicamentos para observar pacientes ingresados en el Hospital de Niños (Córdoba –Argentina) durante 1 mes.Resultados: Durante el mes de estudio ingresaron 680 pacientes, de los cuales 415 (61%) recibieron inhibidores de la acidez gástrica (IAG). De estos, 330 pacientes (79,5%) no presentaron factores de riesgo para desarrollar úlcera por estrés, y en 293 pacientes (70,6%) las indicaciones se consideraron incorrectas. Sólo 81 pacientes (19,5%) presentaron indicaciones y dosis correctas de IAG. Se encontró una relación de la prescripción con el ingreso a quirófano y con el uso concomitante de corticoides a dosis bajas. El consumo innecesario de IAG generó un gasto directo mensual de US$ 470,42.Conclusiones: Este estudio pone de manifiesto una alarmante sobreutilización de IAG en la población pediátrica del Hospital de Niños. Existe una brecha entre las pruebas científicas y la práctica clínica cotidiana en la utilización de IAG. Se deberían implementar estrategias educativas en farmacoterapéutica, utilizando protocolos de actuación y auditorias farmacológicas con posterior evaluación, para mejorar la utilización de medicamentos y otorgar a los pacientes una medicina académica, efectiva, segura y de alta calidad. Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC 2014-03-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/RSD/article/view/6911 10.31052/1853.1180.v16.n1.6911 Revista de Salud Pública; Vol. 16 Núm. 1 (2012); 27-35 1852-9429 1853-1180 10.31052/1853.1180.v16.n1 spa https://revistas.unc.edu.ar/index.php/RSD/article/view/6911/7983 Derechos de autor 1969 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-360 |
| container_title_str |
Revista de Salud Pública |
| language |
Español |
| format |
Artículo revista |
| topic |
Pediatría Farmacoepidemiología Utilización de Medicamentos Profilaxis de Ulcera por Estrés Errores Médicos Antagonistas de Histamina H2 Inhibidores de la Bomba de Protones Pediatrics Pharmacoepidemiology Drug Utilization Stress Ulcer Prophylaxis Medical Errors Histamine H2 Antagonists Proton Pump Inhibitors |
| spellingShingle |
Pediatría Farmacoepidemiología Utilización de Medicamentos Profilaxis de Ulcera por Estrés Errores Médicos Antagonistas de Histamina H2 Inhibidores de la Bomba de Protones Pediatrics Pharmacoepidemiology Drug Utilization Stress Ulcer Prophylaxis Medical Errors Histamine H2 Antagonists Proton Pump Inhibitors Milone, María Caterina Olocco, María Ester Guitart, Xavier Vidal Overuse of Acid-Suppressive Therapy in Pediatric Patients |
| topic_facet |
Pediatría Farmacoepidemiología Utilización de Medicamentos Profilaxis de Ulcera por Estrés Errores Médicos Antagonistas de Histamina H2 Inhibidores de la Bomba de Protones Pediatrics Pharmacoepidemiology Drug Utilization Stress Ulcer Prophylaxis Medical Errors Histamine H2 Antagonists Proton Pump Inhibitors |
| author |
Milone, María Caterina Olocco, María Ester Guitart, Xavier Vidal |
| author_facet |
Milone, María Caterina Olocco, María Ester Guitart, Xavier Vidal |
| author_sort |
Milone, María Caterina |
| title |
Overuse of Acid-Suppressive Therapy in Pediatric Patients |
| title_short |
Overuse of Acid-Suppressive Therapy in Pediatric Patients |
| title_full |
Overuse of Acid-Suppressive Therapy in Pediatric Patients |
| title_fullStr |
Overuse of Acid-Suppressive Therapy in Pediatric Patients |
| title_full_unstemmed |
Overuse of Acid-Suppressive Therapy in Pediatric Patients |
| title_sort |
overuse of acid-suppressive therapy in pediatric patients |
| description |
Objectives: To evaluate prescription patterns of intravenous ranitidine and omeprazole in pediatric patients hospitalized in a children’s hospital, the adequacy of said prescriptions and the costs originated by incorrect prescriptions.Patients and Methods: A study of medication usage was designed to observe all patients hospitalized at Hospital de Niños (Córdoba- Argentina) during one month.Results: During the month of study 680 patients were hospitalized, 415 (61%) of them received acid-suppressive drugs (ASD). From these, 330 patients (79.5%) did not show risk factors to develop stress ulcer and indications were considered incorrect in 293 patients (70.6%). Only 81 patients (19.5%) showed correct indications and doses of ASD. A relationship was found between prescription and access to the operating room along with the concomitant use of corticoid in low doses. The unnecessary consumption of ASD generated a direct monthly expenditure of USD 470.42.Conclusions: This study shows an alarming overuse of ASD in the pediatric population at Hospital de Niños. There exists a gap between scientific tests and everyday clinical practice in ASD use. Educational strategies should be implemented in pharmacotherapy using response protocols and pharmacology audits with posterior assessment to improve the use of medications and provide patients with an effective, safe, high-quality and academic medicine. |
| publisher |
Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC |
| publishDate |
2014 |
| url |
https://revistas.unc.edu.ar/index.php/RSD/article/view/6911 |
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2024-09-03T22:25:03Z |
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