Effect of diabetes on stem cells of the oral cavity. A brief review

Abstract   Tissue engineering is one of the pillars of regeneration techniques in medicine, based on the use of mesenchymal stem cells (MSCs). MSCs have self-renewal and differentiation capabilities in multiple lines, due to which they are multipotent mature cells. MSCs can be spread over...

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Autores principales: Cifuentes Suazo, Gloria, Stange-Dempste, Felipe, Muñoz, Luciano, Cartes-Velasquez, Ricardo
Formato: Artículo revista
Lenguaje:Español
Publicado: Facultad de Odontología 2022
Materias:
stem cells, diabetes, oral cavity, regeneration
células madres
diabetes
cavidad oral
regeneracion
Acceso en línea:https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/38411
Aporte de:
Revista de la Facultad de Odontología de Universidad Nacional de Córdoba
id I10-R335-article-38411
record_format ojs
spelling I10-R335-article-384112025-10-08T14:32:32Z Effect of diabetes on stem cells of the oral cavity. A brief review Efecto de la diabetes en células madres de la cavidad bucal. Una revisión breve Cifuentes Suazo, Gloria Stange-Dempste, Felipe Muñoz, Luciano Cartes-Velasquez, Ricardo stem cells, diabetes, oral cavity, regeneration células madres diabetes cavidad oral regeneracion Abstract   Tissue engineering is one of the pillars of regeneration techniques in medicine, based on the use of mesenchymal stem cells (MSCs). MSCs have self-renewal and differentiation capabilities in multiple lines, due to which they are multipotent mature cells. MSCs can be spread over several tiles, a good amount of MSCs is in the oral cavity, including parts such as the alveolar bone, periodontal ligament, dental pulp, dental follicle, oral mucosa and gums. Despite being a major advance in medical sciences, the use of MSCs may be limited by several factors that affect the biological capabilities of these cells. Considering the oral cavity as one of the main sources of obtaining a high amount MSCs, one of the factors that has great repercussions on oral health and diabetes, the clearest example is the two-way relationship that has periodontitis today. periodontitis is considered the sixth complication of diabetes. Given the above, it is necessary to identify the effects that could also have on the MSCs obtained in the oral cavity, effects that could hinder their use in tissue engineering. The purpose of this review is to describe the effect of diabetes on MSCs in the oral cavity.   Key words: stem cells, diabetes, oral cavity, regeneration       Resumen   La ingeniería tisular es uno de los pilares de técnicas de regeneración en medicina, teniendo su base en el uso de células madres mesenquimales (CMM). Las CMM tienen capacidades de auto renovación y diferenciación en múltiples linajes, esto debido a que son células madres multipotentes. Las CMM se pueden aislar de varios tejidos, una buena fuente de CMM es la cavidad oral, incluyendo partes como el hueso alveolar, ligamento periodontal, pulpa dental, folículo dentario, mucosa oral y encía. A pesar de ser un gran avance en las ciencias médicas, la utilización de las CMM puede verse limitada por varios factores que afecten las capacidades biológicas de estas células. Considerando la cavidad oral como una de las principales fuentes de obtención de gran cantidad de CMM, uno de los factores que tiene grandes repercusiones en la salud oral es la diabetes, el ejemplo más claro es la relación bidireccional que tiene con la periodontitis. Hoy en día la periodontitis se considera la sexta complicación de la diabetes. Dado lo anterior, se hace necesario identificar los efectos que también podría tener sobre las CMM obtenidas en cavidad bucal, efectos que podrían dificultar su uso en ingeniería tisular. El objetivo de esta revisión es describir el efecto de la diabetes en CMM de la cavidad bucal.   Palabras clave: células madre, diabetes, cavidad bucal, regeneración. Facultad de Odontología 2022-08-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/38411 Revista de la Facultad de Odontología; Vol. 32 Núm. 2 (2022): Rev Fac Odont 32(2)-2022-Agosto; 11-15 2545-7594 0325-1071 spa https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/38411/38440 10.25014/ Derechos de autor 2022 Gloria Cifuentes Suazo, Felipe Stange-Dempste, Luciano Muñoz, Ricardo Cartes-Velasquez https://creativecommons.org/licenses/by/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-335
container_title_str Revista de la Facultad de Odontología
language Español
format Artículo revista
topic stem cells, diabetes, oral cavity, regeneration
células madres
diabetes
cavidad oral
regeneracion
spellingShingle stem cells, diabetes, oral cavity, regeneration
células madres
diabetes
cavidad oral
regeneracion
Cifuentes Suazo, Gloria
Stange-Dempste, Felipe
Muñoz, Luciano
Cartes-Velasquez, Ricardo
Effect of diabetes on stem cells of the oral cavity. A brief review
topic_facet stem cells, diabetes, oral cavity, regeneration
células madres
diabetes
cavidad oral
regeneracion
author Cifuentes Suazo, Gloria
Stange-Dempste, Felipe
Muñoz, Luciano
Cartes-Velasquez, Ricardo
author_facet Cifuentes Suazo, Gloria
Stange-Dempste, Felipe
Muñoz, Luciano
Cartes-Velasquez, Ricardo
author_sort Cifuentes Suazo, Gloria
title Effect of diabetes on stem cells of the oral cavity. A brief review
title_short Effect of diabetes on stem cells of the oral cavity. A brief review
title_full Effect of diabetes on stem cells of the oral cavity. A brief review
title_fullStr Effect of diabetes on stem cells of the oral cavity. A brief review
title_full_unstemmed Effect of diabetes on stem cells of the oral cavity. A brief review
title_sort effect of diabetes on stem cells of the oral cavity. a brief review
description Abstract   Tissue engineering is one of the pillars of regeneration techniques in medicine, based on the use of mesenchymal stem cells (MSCs). MSCs have self-renewal and differentiation capabilities in multiple lines, due to which they are multipotent mature cells. MSCs can be spread over several tiles, a good amount of MSCs is in the oral cavity, including parts such as the alveolar bone, periodontal ligament, dental pulp, dental follicle, oral mucosa and gums. Despite being a major advance in medical sciences, the use of MSCs may be limited by several factors that affect the biological capabilities of these cells. Considering the oral cavity as one of the main sources of obtaining a high amount MSCs, one of the factors that has great repercussions on oral health and diabetes, the clearest example is the two-way relationship that has periodontitis today. periodontitis is considered the sixth complication of diabetes. Given the above, it is necessary to identify the effects that could also have on the MSCs obtained in the oral cavity, effects that could hinder their use in tissue engineering. The purpose of this review is to describe the effect of diabetes on MSCs in the oral cavity.   Key words: stem cells, diabetes, oral cavity, regeneration      
publisher Facultad de Odontología
publishDate 2022
url https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/38411
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first_indexed 2024-09-03T21:16:26Z
last_indexed 2025-10-10T05:06:45Z
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