Mast cell population in salivary glands of rats which underwent castration and DMBA application

castration and simultaneous application of DMBA. Wistar young males were used, in groups of five animales each. They weresacriíiced lZ, Z3 and Z8 days after the experlment was started. The glands werediss~cted and fixed in 10 % formol at Ph. 7 in arder to be . studiedmorphohistochemically and histom...

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Detalles Bibliográficos
Autores principales: Fonseca, M, Ferraris, M. E., De David Rins, M L, Gendelman, H
Formato: Artículo revista
Lenguaje:Español
Publicado: Facultad de Odontología 2018
Materias:
Mastocitos
Glándulas Salivales
Ratas
DMBA
Mastocytosis
Salivary Glands
Rats
9
10-Dimethyl-1
2-benzanthracene
Acceso en línea:https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/21369
Aporte de:
Revista de la Facultad de Odontología de Universidad Nacional de Córdoba
id I10-R335-article-21369
record_format ojs
spelling I10-R335-article-213692018-10-02T12:08:31Z Mast cell population in salivary glands of rats which underwent castration and DMBA application Población mastocitaria en glándulas salivales de ratas sometidas a DMBA y castración Fonseca, M Ferraris, M. E. De David Rins, M L Gendelman, H Mastocitos Glándulas Salivales Ratas DMBA Mastocytosis Salivary Glands Rats 9 10-Dimethyl-1 2-benzanthracene castration and simultaneous application of DMBA. Wistar young males were used, in groups of five animales each. They weresacriíiced lZ, Z3 and Z8 days after the experlment was started. The glands werediss~cted and fixed in 10 % formol at Ph. 7 in arder to be . studiedmorphohistochemically and histometrically. The number of mast cells increased in the sublingual gland (SLG) at all the time perlods studied, outnumbering considerably the cell population in the sub maxillary gland (SMG) lZ days after the animals had been castrated. When comparing uncastrated · animals with castrated ones, it is noticed that the most importantdifíerences in the mast cell population appear in the SLG. With application of DMBA and simultaneous castration, it is observed that the sublingual gland (which normally has very little receptivity to DMBA in un castrated animals) experiences an atypical tissue response accompanied by anincrease in its mast cell population En el presente trabajo se cuantifican mastocitos en relación a las modificaciones histolÓgicas de las glándulas salivales de ratas sometidas a la castracióñy aplicación simultánea de DMBA. Se utilizaron machos jóvenes Wistar, en grupos de cinco animales cada uno. Se sacrificaron a los lZ, Z3 y Z8 dÍas de iniciada la experiencia. Se disecaron las glándulas y se fijan en formol a Ph. 7 para su estudio morfohistoquímico e histométrico. En la glándula sublingual (GSL) se incrementa el número de mastocitos en todos los plazos estudiados, superando significativamente la población celular de la glándula submaxilar (GSM) a los lZ dÍas de castrados. Al comparar animales sin castrar y castrados se advierte que las diferencias más notables de la población mastocitaria se presentan en GSL. Con DMBA y castración simultánea se observa que la glándula sublingual (de por sí muy poco receptiva para el DMBA en los animales sin castrar) condiciona la respuesta tisular atípica de la glándula al efecto del cancerígeno y por endea la población mastocitaria. Facultad de Odontología 2018-09-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/21369 Revista de la Facultad de Odontología; Vol. 15. Enero - Diciembre (1987); 38-48 2545-7594 0325-1071 spa https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/21369/20889 10.25014/RevFacOdont27166
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-335
container_title_str Revista de la Facultad de Odontología
language Español
format Artículo revista
topic Mastocitos
Glándulas Salivales
Ratas
DMBA
Mastocytosis
Salivary Glands
Rats
9
10-Dimethyl-1
2-benzanthracene
spellingShingle Mastocitos
Glándulas Salivales
Ratas
DMBA
Mastocytosis
Salivary Glands
Rats
9
10-Dimethyl-1
2-benzanthracene
Fonseca, M
Ferraris, M. E.
De David Rins, M L
Gendelman, H
Mast cell population in salivary glands of rats which underwent castration and DMBA application
topic_facet Mastocitos
Glándulas Salivales
Ratas
DMBA
Mastocytosis
Salivary Glands
Rats
9
10-Dimethyl-1
2-benzanthracene
author Fonseca, M
Ferraris, M. E.
De David Rins, M L
Gendelman, H
author_facet Fonseca, M
Ferraris, M. E.
De David Rins, M L
Gendelman, H
author_sort Fonseca, M
title Mast cell population in salivary glands of rats which underwent castration and DMBA application
title_short Mast cell population in salivary glands of rats which underwent castration and DMBA application
title_full Mast cell population in salivary glands of rats which underwent castration and DMBA application
title_fullStr Mast cell population in salivary glands of rats which underwent castration and DMBA application
title_full_unstemmed Mast cell population in salivary glands of rats which underwent castration and DMBA application
title_sort mast cell population in salivary glands of rats which underwent castration and dmba application
description castration and simultaneous application of DMBA. Wistar young males were used, in groups of five animales each. They weresacriíiced lZ, Z3 and Z8 days after the experlment was started. The glands werediss~cted and fixed in 10 % formol at Ph. 7 in arder to be . studiedmorphohistochemically and histometrically. The number of mast cells increased in the sublingual gland (SLG) at all the time perlods studied, outnumbering considerably the cell population in the sub maxillary gland (SMG) lZ days after the animals had been castrated. When comparing uncastrated · animals with castrated ones, it is noticed that the most importantdifíerences in the mast cell population appear in the SLG. With application of DMBA and simultaneous castration, it is observed that the sublingual gland (which normally has very little receptivity to DMBA in un castrated animals) experiences an atypical tissue response accompanied by anincrease in its mast cell population
publisher Facultad de Odontología
publishDate 2018
url https://revistas.unc.edu.ar/index.php/RevFacOdonto/article/view/21369
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AT ferrarisme mastcellpopulationinsalivaryglandsofratswhichunderwentcastrationanddmbaapplication
AT dedavidrinsml mastcellpopulationinsalivaryglandsofratswhichunderwentcastrationanddmbaapplication
AT gendelmanh mastcellpopulationinsalivaryglandsofratswhichunderwentcastrationanddmbaapplication
AT fonsecam poblacionmastocitariaenglandulassalivalesderatassometidasadmbaycastracion
AT ferrarisme poblacionmastocitariaenglandulassalivalesderatassometidasadmbaycastracion
AT dedavidrinsml poblacionmastocitariaenglandulassalivalesderatassometidasadmbaycastracion
AT gendelmanh poblacionmastocitariaenglandulassalivalesderatassometidasadmbaycastracion
first_indexed 2024-09-03T21:15:18Z
last_indexed 2024-09-03T21:15:18Z
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