Obstetric and neonatal outcomes in pregnancies conceived by assisted reproductive technology in an Argentine cohort.

Introduction: Since its introduction in clinical practice in 1981, pregnancies conceived by assisted reproductive techniques (ART) are an increasing proportion of all pregnancies, presenting particular challenges. Objective: To analyze the maternal-fetal outcomes of pregnancies conceived by ART in a...

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Detalles Bibliográficos
Autores principales: Diez Brito, Macarena, Sevillano, Gonzalo, Negri, Florence, Mongelos, Miracles, Negri, Florencia, Mongelos, Milagros, Izbizky, Gustavo, Negri, Florença, Mongelos, Milgros
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2024
Materias:
reproductive techniques, assisted
pregnancy complications
pregnancy outcome
perinatal care
técnicas reproductivas asistidas
complicaciones del embarazo
resultado del embarazo
atención perinatal
técnicas de reprodução assistida
complicações na gravidez
resultado da gravidez
assistência perinatal
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/44425
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
Descripción
Sumario:Introduction: Since its introduction in clinical practice in 1981, pregnancies conceived by assisted reproductive techniques (ART) are an increasing proportion of all pregnancies, presenting particular challenges. Objective: To analyze the maternal-fetal outcomes of pregnancies conceived by ART in a single center in Argentina. Material and methods: Retrospective cohort of pregnancies conceived by ART who attended their delivery in a private university hospital through a review of records. Results: The incidence of composite primary maternal outcome was 40,1% (282/703), with hypertensive disease of pregnancy (21%) being the most frequent presenting pathology.In the multivariate analysis, age > 40 (OR 2,79; 95%CI: 1,82-4,26), chronic hypertension (OR 10,59; 95% CI: 2,81-39,86), twin pregnancy (OR 8,94; 95% CI: 5,39 – 14,80) and oocyte donation (OR 1,54; 95% CI: 1,04 – 2,27) were significantly associated with the maternal primary outcome. The incidence of the composite neonatal fetal primary outcome was 56,7% (468/824), with a prematurity rate of 34,5% (252/803).  In the multivariate analysis of the composite outcome of the neonatal fetus, twin pregnancy (OR 7,08; 95% CI: 3,48 – 14,39) and other complications related to prematurity were statistically significantly associated with the composite outcome. Conclusions: Pregnancies conceived by ART show a significant increase in adverse maternal outcomes, mainly hypertension, and fetal and neonatal outcomes (prematurity, malformations, and admission to the intensive care unit).

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