CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions

CT-guided transthoracic biopsy is a minimally invasive technique frequently employed for obtaining histopathological diagnoses of lung lesions. While certain complications may arise from this procedure, the low incidence of major complications underscores its safety. This study aims to analyze...

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Autores principales: Jubete, M, Guzmán Souto, ALV, Castrill´ón, ME
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023
Materias:
image-guided biopsy
tomography
lung injury
pneumothorax
subcutaneous emphysema
biopsia guiada por imagen
tomografía
lesión pulmonar
neumotórax
enfisema subcutáneo
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/42832
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-42832
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic image-guided biopsy
tomography
lung injury
pneumothorax
subcutaneous emphysema
biopsia guiada por imagen
tomografía
lesión pulmonar
neumotórax
enfisema subcutáneo
spellingShingle image-guided biopsy
tomography
lung injury
pneumothorax
subcutaneous emphysema
biopsia guiada por imagen
tomografía
lesión pulmonar
neumotórax
enfisema subcutáneo
Jubete, M
Guzmán Souto, ALV
Castrill´ón, ME
CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions
topic_facet image-guided biopsy
tomography
lung injury
pneumothorax
subcutaneous emphysema
biopsia guiada por imagen
tomografía
lesión pulmonar
neumotórax
enfisema subcutáneo
author Jubete, M
Guzmán Souto, ALV
Castrill´ón, ME
author_facet Jubete, M
Guzmán Souto, ALV
Castrill´ón, ME
author_sort Jubete, M
title CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions
title_short CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions
title_full CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions
title_fullStr CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions
title_full_unstemmed CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions
title_sort ct characteristics predictive of complications during ct-guided transthoracic biopsies of lung lesions
description CT-guided transthoracic biopsy is a minimally invasive technique frequently employed for obtaining histopathological diagnoses of lung lesions. While certain complications may arise from this procedure, the low incidence of major complications underscores its safety. This study aims to analyze predictive CT characteristics and the patients' pathological history regarding the development of complications during CT-guided transthoracic biopsies. A retrospective, observational, cross-sectional, and analytical study was conducted on 43 patients who underwent CT-guided transthoracic biopsies. The study involved evaluating the attenuation, size, location, and distance of the lesion from the pleura. Additionally, the occurrence of pneumothorax and subcutaneous emphysema was assessed using control CT images acquired immediately after the biopsy. Patient demographics, including age, sex, pathological history, and biopsy results, were also collected. This study employed various statistical measures, such as absolute and relative frequencies, means, standard deviations, minimum and maximum values, and associations among variables, to describe the data. Among the 43 patients studied, 9 (21%) developed pneumothorax. Notably, 4 of these cases had lesions located in direct contact with the pleura (0 mm distance) (p-value: 0.0205; odds ratio [OR]: 5.83, 95% confidence interval [CI]: 1.29-26.49). A statistically significant correlation was observed between the distance of the lesion from the pleura and the occurrence of pneumothorax (p=0.0390). Subcutaneous emphysema was identified in 20 (47%) patients after the CT-guided biopsy, with 13 of these cases occurring in female patients (p-value: 0.0061; OR: 6.14, 95% CI: 1.68-22.49). Other evaluated variables did not exhibit statistically significant associations with the development of pneumothorax or subcutaneous emphysema as complications of the biopsy. The observed association between the distance of the lesion from the pleura and the occurrence of pneumothorax aligns with findings derived of other studies. Although patient age has been reported as a significant risk factor in complications in prior research, it did not emerge as a significant variable in our study results. Both pneumothorax and subcutaneous emphysema were demonstrated to be frequent complications following CT-guided transthoracic biopsies. In addition to these complications, the procedure proved effective in achieving histopathological diagnoses of lung lesions.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2023
url https://revistas.unc.edu.ar/index.php/med/article/view/42832
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spelling I10-R327-article-428322023-10-19T21:18:55Z CT characteristics predictive of complications during CT-guided transthoracic biopsies of lung lesions Características tomográficas predictivas de complicaciones durante la biopsia de lesiones pulmonares por punción transtorácica guiada por tomografía computada Jubete, M Guzmán Souto, ALV Castrill´ón, ME image-guided biopsy tomography lung injury pneumothorax subcutaneous emphysema biopsia guiada por imagen tomografía lesión pulmonar neumotórax enfisema subcutáneo CT-guided transthoracic biopsy is a minimally invasive technique frequently employed for obtaining histopathological diagnoses of lung lesions. While certain complications may arise from this procedure, the low incidence of major complications underscores its safety. This study aims to analyze predictive CT characteristics and the patients' pathological history regarding the development of complications during CT-guided transthoracic biopsies. A retrospective, observational, cross-sectional, and analytical study was conducted on 43 patients who underwent CT-guided transthoracic biopsies. The study involved evaluating the attenuation, size, location, and distance of the lesion from the pleura. Additionally, the occurrence of pneumothorax and subcutaneous emphysema was assessed using control CT images acquired immediately after the biopsy. Patient demographics, including age, sex, pathological history, and biopsy results, were also collected. This study employed various statistical measures, such as absolute and relative frequencies, means, standard deviations, minimum and maximum values, and associations among variables, to describe the data. Among the 43 patients studied, 9 (21%) developed pneumothorax. Notably, 4 of these cases had lesions located in direct contact with the pleura (0 mm distance) (p-value: 0.0205; odds ratio [OR]: 5.83, 95% confidence interval [CI]: 1.29-26.49). A statistically significant correlation was observed between the distance of the lesion from the pleura and the occurrence of pneumothorax (p=0.0390). Subcutaneous emphysema was identified in 20 (47%) patients after the CT-guided biopsy, with 13 of these cases occurring in female patients (p-value: 0.0061; OR: 6.14, 95% CI: 1.68-22.49). Other evaluated variables did not exhibit statistically significant associations with the development of pneumothorax or subcutaneous emphysema as complications of the biopsy. The observed association between the distance of the lesion from the pleura and the occurrence of pneumothorax aligns with findings derived of other studies. Although patient age has been reported as a significant risk factor in complications in prior research, it did not emerge as a significant variable in our study results. Both pneumothorax and subcutaneous emphysema were demonstrated to be frequent complications following CT-guided transthoracic biopsies. In addition to these complications, the procedure proved effective in achieving histopathological diagnoses of lung lesions. La biopsia pulmonar por punción transtorácica guiada por tomografía computada (TC) es una técnica mínimamente invasiva utilizada para arribar al diagnóstico histopatológico de lesiones pulmonares. Tras este procedimiento pueden desarrollarse algunas complicaciones, sin embargo, la baja tasa de complicaciones mayores garantizaría la seguridad de la técnica. El objetivo de este estudio es analizar las características tomográficas predictivas y antecedentes personales y patológicos para el desarrollo de complicaciones de la biopsia por punción transtorácica guiada por TC. Estudio retrospectivo, observacional, transversal y analítico de 43 pacientes sometidos a punciones transtorácicas guiadas por TC. Se analizaron la atenuación, tamaño, localización y distancia de la pleura de las lesiones pulmonares, así como la presencia de neumotórax y enfisema subcutáneo en las imágenes tomográficas de control post-punción. Se registró el sexo, edad, antecedentes personales patológicos y resultados de anatomía patológica de los pacientes. Se describieron frecuencias absolutas y relativas, media, desvío estándar, valores mínimo-máximo y asociación entre las variables. De los 43 pacientes estudiados, 9 (21%) desarrollaron neumotórax; y de estos, 4 presentaron lesiones en contacto con la pleura (0 mm de distancia) (p-valor: 0,0205; OR: 5,83 IC95%: 1,29-26,49). Se obtuvo una asociación estadísticamente significativa entre la distancia a la pleura de la lesión y la aparición de neumotórax (p=0,0390). 20 pacientes desarrollaron enfisema subcutáneo (47%), y de ellos, 13 fueron mujeres (p-valor: 0,0061; OR: 6,14, IC95%: 1,68-22,49). El resto de las variables analizadas no representaron una asociación estadísticamente significativa para neumotórax o enfisema subcutáneo como complicación de la punción.  La asociación entre la distancia a la pleura de la lesión y el desarrollo de neumotórax es compatible con resultados de otros autores. Mientras que la edad representó una asociación estadísticamente significativa para la aparición de complicaciones en otros estudios, en nuestros resultados esta variable no fue significativa. Tanto el neumotórax como el enfisema subcutáneo han demostrado ser complicaciones frecuentemente desarrolladas tras la ejecución de una punción guiada por TC. A pesar de las complicaciones descritas, la biopsia por punción transtorácica ha resultado eficaz para el diagnóstico histopatológico de lesiones pulmonares. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-10-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/42832 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 (2023): Suplemento JIC XXIV Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 (2023): Suplemento JIC XXIV Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 (2023): Suplemento JIC XXIV 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/42832/42886 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0

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