Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes

Introduction: A progressive increase in the age of women at first pregnancy is observed, a situation that has been associated with a greater risk of adverse maternal and perinatal effects. Objective: The aim of this study was to describe the characteristics and the maternal and perinatal outcomes of...

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Detalles Bibliográficos
Autores principales: Carducci, Maria Eugenia, Izbizky, Gustavo
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2024
Materias:
maternal age
pregnancy complications
pregnancy outcome
perinatal care
edad materna
complicaciones del embarazo
resultado del embarazo
atención perinatal
idade materna
complicações na gravidez
resultado da gravidez
assistência perinatal
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/41447
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-41447
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic maternal age
pregnancy complications
pregnancy outcome
perinatal care
edad materna
complicaciones del embarazo
resultado del embarazo
atención perinatal
idade materna
complicações na gravidez
resultado da gravidez
assistência perinatal
spellingShingle maternal age
pregnancy complications
pregnancy outcome
perinatal care
edad materna
complicaciones del embarazo
resultado del embarazo
atención perinatal
idade materna
complicações na gravidez
resultado da gravidez
assistência perinatal
Carducci, Maria Eugenia
Izbizky, Gustavo
Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
topic_facet maternal age
pregnancy complications
pregnancy outcome
perinatal care
edad materna
complicaciones del embarazo
resultado del embarazo
atención perinatal
idade materna
complicações na gravidez
resultado da gravidez
assistência perinatal
author Carducci, Maria Eugenia
Izbizky, Gustavo
author_facet Carducci, Maria Eugenia
Izbizky, Gustavo
author_sort Carducci, Maria Eugenia
title Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
title_short Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
title_full Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
title_fullStr Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
title_full_unstemmed Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
title_sort advanced maternal age as a risk factor for adverse maternal and perinatal outcomes
description Introduction: A progressive increase in the age of women at first pregnancy is observed, a situation that has been associated with a greater risk of adverse maternal and perinatal effects. Objective: The aim of this study was to describe the characteristics and the maternal and perinatal outcomes of nulliparas of 40 years and older and compare them with those of nulliparas under 40. Study design: This was a retrospective cohort analysis of a database of pregnancy population who had attended their deliveries in a private university hospital. Results: An association was observed between maternal age ≥ 40 with the maternal compound adverse outcome (OR 1,3; 95% CI: 1,1-1,6), gestational diabetes (OR 3,6; 95% CI: 1,80-3,7), hypertensive disorders/preeclampsia (OR 2,2; 95% CI: 1,6-3,1) and postpartum hemorrhage (4,7; 95% CI: 1,2-16,3), with advanced maternal age persisting as an independent risk factor for the maternal compound adverse outcome (OR 1,3; 95% CI: 1,1 -1,6) and the perinatal compound adverse outcome (OR 1,40; 95% CI: 1,2-1,7) in the multivariate analysis. A higher rate of preterm birth was observed in the group of older nulliparas (OR 1,6; 95% CI: 1,3-2,0) with a higher requirement for admission to NICU for their newborns (OR 1,3; 95% CI: 1,0-1,8). Conclusions: Women with advanced maternal age constitute a high-risk population, whose attention and follow-up would require a differential approach aiming to improve maternal and perinatal outcomes.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2024
url https://revistas.unc.edu.ar/index.php/med/article/view/41447
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spelling I10-R327-article-414472024-04-24T19:00:41Z Advanced maternal age as a risk factor for adverse maternal and perinatal outcomes Edad materna avanzada como factor de riesgo de resultados adversos maternos y perinatales Idade materna avançada como fator de risco para desfechos maternos e perinatais adversos Carducci, Maria Eugenia Izbizky, Gustavo maternal age pregnancy complications pregnancy outcome perinatal care edad materna complicaciones del embarazo resultado del embarazo atención perinatal idade materna complicações na gravidez resultado da gravidez assistência perinatal Introduction: A progressive increase in the age of women at first pregnancy is observed, a situation that has been associated with a greater risk of adverse maternal and perinatal effects. Objective: The aim of this study was to describe the characteristics and the maternal and perinatal outcomes of nulliparas of 40 years and older and compare them with those of nulliparas under 40. Study design: This was a retrospective cohort analysis of a database of pregnancy population who had attended their deliveries in a private university hospital. Results: An association was observed between maternal age ≥ 40 with the maternal compound adverse outcome (OR 1,3; 95% CI: 1,1-1,6), gestational diabetes (OR 3,6; 95% CI: 1,80-3,7), hypertensive disorders/preeclampsia (OR 2,2; 95% CI: 1,6-3,1) and postpartum hemorrhage (4,7; 95% CI: 1,2-16,3), with advanced maternal age persisting as an independent risk factor for the maternal compound adverse outcome (OR 1,3; 95% CI: 1,1 -1,6) and the perinatal compound adverse outcome (OR 1,40; 95% CI: 1,2-1,7) in the multivariate analysis. A higher rate of preterm birth was observed in the group of older nulliparas (OR 1,6; 95% CI: 1,3-2,0) with a higher requirement for admission to NICU for their newborns (OR 1,3; 95% CI: 1,0-1,8). Conclusions: Women with advanced maternal age constitute a high-risk population, whose attention and follow-up would require a differential approach aiming to improve maternal and perinatal outcomes. Introducción: Se observa un progresivo aumento en la edad de las mujeres al primer embarazo, situación que se ha asociado con mayor riesgo de efectos maternos y perinatales adversos. Objetivo: Describir las características y los resultados maternos y perinatales de nulíparas de 40 años y mayores y compararlos con los de nulíparas menores de 40. Material y métodos: Cohorte retrospectiva de embarazos que atendieron su parto en un hospital privado universitario mediante revisión de registros. Resultados: Se observó asociación entre la edad materna ≥ 40 con el resultado adverso compuesto materno (OR 1.3; IC 95%: 1,1-1,6), DBT g (OR 3,6; IC 95%: 1,8-3,7), enfermedad hipertensiva/PE (OR 2,2; IC 95%: 1,6-3,1) y hemorragia postparto (4,7; IC 95%: 1,2-16.3), persistiendo la edad avanzada como factor de riesgo independiente para el resultado adverso compuesto materno (OR 1,3; IC 95%: 1,1-1,6) y perinatal (OR 1,4; IC 95%: 1,2-1,7) en el análisis multivariado. Se observó mayor tasa de parto pretérmino en el grupo de nulíparas añosas (OR 1,6; IC 95%: 1,3-2,0) con mayor requerimiento de ingreso a UCIN para sus recién nacidos (OR 1,3; IC 95%: 1,0-1,8). Conclusiones: Las mujeres con edad materna avanzada constituyen una población de alto riesgo, cuya atención y seguimiento requeriría un enfoque diferencial que tenga como objetivo mejorar los resultados maternos y perinatales. Introdução: Observa-se um aumento progressivo da idade das mulheres à primeira gravidez, situação que tem sido associada a um maior risco de efeitos adversos maternos e perinatais. Objetivo: Descrever as características e desfechos maternos e perinatais de nulíparas com 40 anos ou mais e compará-los com os de nulíparas com menos de 40 anos. Material e métodos: Coorte retrospectiva de gestações que deram à luz em um hospital universitário privado por meio de revisão de prontuários. Resultados: Observou-se associação entre idade materna ≥ 40 anos com o desfecho adverso composto materno (OR 1,3; IC 95%: 1,1-1,6), DBT g (OR 3,6; IC 95%: 1,8-3,7), doença hipertensiva/EP ( OR 2,2; IC 95%: 1,6-3,1) e hemorragia pós-parto (4,7; IC 95%: 1,2-16,3), com idade avançada persistindo como fator de risco independente para desfecho adverso composto materno (OR 1,3; IC 95%: 1,1 -1,6) e perinatal (OR 1,4; IC 95%: 1,2-1,7) na análise multivariada. Maior taxa de parto prematuro foi observada no grupo de idosas nulíparas (OR 1,6; IC 95%: 1,3-2,0) com maior necessidade de internação em UTIN para seus recém-nascidos (OR 1,3; IC 95%: 1,0-1,8 ). Conclusões: As mulheres com idade materna avançada constituem uma população de alto risco, cujo cuidado e acompanhamento exigiriam uma abordagem diferenciada que vise melhorar os resultados maternos e perinatais. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2024-03-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text/html application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/41447 10.31053/1853.0605.v81.n1.41447 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 81 No. 1 (2024); 24-39 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 81 Núm. 1 (2024); 24-39 Revista da Faculdade de Ciências Médicas de Córdoba; v. 81 n. 1 (2024); 24-39 1853-0605 0014-6722 10.31053/1853.0605.v81.n1 spa https://revistas.unc.edu.ar/index.php/med/article/view/41447/44626 https://revistas.unc.edu.ar/index.php/med/article/view/41447/44751 Derechos de autor 2024 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0

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