Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.

COVID-19 vaccination aids pandemic limitation. In Argentina, three vaccines are approved, and healthcare workers are priorized (HCWs). The aim was to determine the effectiveness of COVID-19 vaccines, analyzing change in Immunoglobulin G levels and the incidence of new COVID-19 cases up to 12 months...

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Autores principales: Pagotto, Vanina, Seoane, Facundo, Arrigo, Diego, Ardiles, Victoria, Asprea, Valeria, De Florio, Florencia, Ferloni, Analia, Aliperti, Valeria
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2024
Materias:
COVID-19 serological testing
health personnel
COVID-19 vaccines
pruebas serológicas COVID-19
fuerza laboral en salud
vacunas contra la COVID-19
testes sorológicos COVID-19
mão de obra em saúde
vacinas contra COVID-19
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/41155
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
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institution Universidad Nacional de Córdoba
institution_str I-10
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container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic COVID-19 serological testing
health personnel
COVID-19 vaccines
pruebas serológicas COVID-19
fuerza laboral en salud
vacunas contra la COVID-19
testes sorológicos COVID-19
mão de obra em saúde
vacinas contra COVID-19
spellingShingle COVID-19 serological testing
health personnel
COVID-19 vaccines
pruebas serológicas COVID-19
fuerza laboral en salud
vacunas contra la COVID-19
testes sorológicos COVID-19
mão de obra em saúde
vacinas contra COVID-19
Pagotto, Vanina
Seoane, Facundo
Arrigo, Diego
Ardiles, Victoria
Asprea, Valeria
De Florio, Florencia
Ferloni, Analia
Aliperti, Valeria
Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.
topic_facet COVID-19 serological testing
health personnel
COVID-19 vaccines
pruebas serológicas COVID-19
fuerza laboral en salud
vacunas contra la COVID-19
testes sorológicos COVID-19
mão de obra em saúde
vacinas contra COVID-19
author Pagotto, Vanina
Seoane, Facundo
Arrigo, Diego
Ardiles, Victoria
Asprea, Valeria
De Florio, Florencia
Ferloni, Analia
Aliperti, Valeria
author_facet Pagotto, Vanina
Seoane, Facundo
Arrigo, Diego
Ardiles, Victoria
Asprea, Valeria
De Florio, Florencia
Ferloni, Analia
Aliperti, Valeria
author_sort Pagotto, Vanina
title Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.
title_short Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.
title_full Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.
title_fullStr Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.
title_full_unstemmed Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.
title_sort effectiveness and safety of covid-19 vaccines in healthcare workers in buenos aires city, argentina.
description COVID-19 vaccination aids pandemic limitation. In Argentina, three vaccines are approved, and healthcare workers are priorized (HCWs). The aim was to determine the effectiveness of COVID-19 vaccines, analyzing change in Immunoglobulin G levels and the incidence of new COVID-19 cases up to 12 months after the second dose. Methods: Prospective cohort of HCWs between March 2021- 2022.  COVIDAR IgG test was used to measure antibodies. A mixed-effects model was employed to compare the levels of immunoglobulin G at different time points, Kaplan Meier was used to estimate incident COVID-19 cases. Results: 82 participants were included Adverse events were frequent but mild.  All participant showed positive antibody at 12 months. Antibodies levels showed an increase one year after 2nd dose. Sinopharm took a long time to yield positive results.  More than half of the people had mild COVID-19 disease. Conclusion COVID-19 vaccines are safe and effective.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2024
url https://revistas.unc.edu.ar/index.php/med/article/view/41155
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spelling I10-R327-article-411552024-04-24T19:00:41Z Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina. Efectividad y seguridad de las vacunas contra la Covid-19 en trabajadores de la salud en la Ciudad de Buenos Aires, Argentina. Efetividade e segurança das vacinas COVID-19 em trabalhadores da saúde na cidade de Buenos Aires, Argentina. Pagotto, Vanina Seoane, Facundo Arrigo, Diego Ardiles, Victoria Asprea, Valeria De Florio, Florencia Ferloni, Analia Aliperti, Valeria COVID-19 serological testing health personnel COVID-19 vaccines pruebas serológicas COVID-19 fuerza laboral en salud vacunas contra la COVID-19 testes sorológicos COVID-19 mão de obra em saúde vacinas contra COVID-19 COVID-19 vaccination aids pandemic limitation. In Argentina, three vaccines are approved, and healthcare workers are priorized (HCWs). The aim was to determine the effectiveness of COVID-19 vaccines, analyzing change in Immunoglobulin G levels and the incidence of new COVID-19 cases up to 12 months after the second dose. Methods: Prospective cohort of HCWs between March 2021- 2022.  COVIDAR IgG test was used to measure antibodies. A mixed-effects model was employed to compare the levels of immunoglobulin G at different time points, Kaplan Meier was used to estimate incident COVID-19 cases. Results: 82 participants were included Adverse events were frequent but mild.  All participant showed positive antibody at 12 months. Antibodies levels showed an increase one year after 2nd dose. Sinopharm took a long time to yield positive results.  More than half of the people had mild COVID-19 disease. Conclusion COVID-19 vaccines are safe and effective. La vacunación COVID-19 ayuda a limitar la pandemia. En Argentina, se aprobaron tres vacunas y se priorizó a los trabajadores de la salud (TDS). El objetivo fue determinar la efectividad de las vacunas COVID-19, analizando el cambio en los niveles de Inmunoglobulina G y la incidencia de nuevos casos de COVID-19 hasta 12 meses después de la segunda dosis. Métodos: Cohorte prospectiva de TDS entre marzo de 2021 y 2022. Se utilizó la prueba COVIDAR IgG para medir los anticuerpos. Se empleó un modelo de efectos mixtos para comparar los niveles de inmunoglobulina G en diferentes puntos temporales, se utilizó Kaplan Meier para estimar los casos de COVID-19 incidentes. Resultados: se incluyeron 82 participantes. Los eventos adversos fueron frecuentes pero leves. Todos los participantes mostraron anticuerpos positivos a los 12 meses. Los niveles de anticuerpos mostraron un aumento un año después de la segunda dosis. Sinopharm tardó mucho tiempo en arrojar resultados positivos. Más de la mitad de las personas tuvieron una enfermedad leve de COVID-19. Conclusión: Las vacunas COVID-19 son seguras y efectivas. A vacinação contra a COVID-19 ajuda a limitar a pandemia. Na Argentina, foram aprovadas três vacinas e os trabalhadores da saúde (TDS) foram priorizados. O objetivo foi determinar a eficácia das vacinas COVID-19, analisando a mudança nos níveis de imunoglobulina G e a incidência de novos casos de COVID-19 até 12 meses após a segunda dose. Métodos: Coorte prospectiva de TDS entre março de 2021 e 2022. Foi utilizado o teste COVIDAR IgG para medir os anticorpos. Foi utilizado um modelo de efeitos mistos para comparar os níveis de imunoglobulina G em diferentes pontos temporais, e o Kaplan Meier foi utilizado para estimar os casos de COVID-19 incidentes. Resultados: foram incluídos 82 participantes. Os eventos adversos foram frequentes, mas leves. Todos os participantes apresentaram anticorpos positivos após 12 meses. Os níveis de anticorpos mostraram um aumento um ano após a segunda dose. A vacina Sinopharm demorou muito tempo para apresentar resultados positivos. Mais da metade das pessoas tiveram uma doença leve de COVID-19. Conclusão: As vacinas COVID-19 são seguras e eficazes. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2024-03-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Text, table and figure Texto, figura y tabla texto, tablea, figura text/html application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/41155 10.31053/1853.0605.v81.n1.41155 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 81 No. 1 (2024); 115-127 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 81 Núm. 1 (2024); 115-127 Revista da Faculdade de Ciências Médicas de Córdoba; v. 81 n. 1 (2024); 115-127 1853-0605 0014-6722 10.31053/1853.0605.v81.n1 spa https://revistas.unc.edu.ar/index.php/med/article/view/41155/44882 https://revistas.unc.edu.ar/index.php/med/article/view/41155/44764 Derechos de autor 2024 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0

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